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Allergic reactions reaction times

Sensitizer A sensitizer is defined by OSHA as "a chemical that causes a substantial proportion of exposed people or animals to develop an allergic reaction in normal tissue after repeated exposure to the chemical." The condition of being sensitized to a chemical is also called chemical hypersensitivity. Certain chemicals have no immediate health effect. But if you are exposed to them several times, they can make you allergic or sensitive to other chemicals. A classic example is formaldehyde (HCHO). Typical reactions to sensitizers can include skin disorders such as eczema. When working with sensitizers, always use proper protective equipment such as gloves, respirators, etc. Once you are sensitized to a particular chemical, even minute amounts will cause symptoms. Sensitization is usually a lifelong effect. [Pg.547]

There have been numerous reports of possible allergic reactions to mercury and mercury salts and to the mercury, silver and copper in dental amalgam as well as to amalgam corrosion products Studies of the release of mercury by amalgams into distilled water, saline and artificial saliva tend to be conflicting and contradictory but, overall, the data indicate that mercury release drops with time due to film formation and is less than the acceptable daily intake for mercury in food . Further, while metallic mercury can sensitise, sensitisation of patients to mercury by dental amalgam appears to be a rare occurrence. Nevertheless, there is a growing trend to develop polymer-based posterior restorative materials in order to eliminate the use of mercury in dentistry. [Pg.461]

At the time when allergic reactions were classified little was known about cellular reactions, thus it appears appropriate today to divide this reaction type in two subgroups. [Pg.60]

This mediator, apart from aggregating platelets and stimulating many cells types, is a very potent mediator in allergic reactions causing bronchoconstriction with a 1,000 times more potency than histamine. It is able to increase vascular permeability and cause chemotaxis and degranulation of eosinophils and neutrophils [14-16]. [Pg.128]

All monoclonal antibodies end in the suffix -mab. The syllable before -mab indicates the source of the monoclonal antibody (see Table 85-4). When administering an antibody for the first time, one should consider the source. The less humanized an antibody, the greater is the chance for the patient to have an allergic-type reaction to the antibody. The more humanized the antibody, the lower is the risk of a reaction. The severity of the reactions may range from fever and chills to life-threatening allergic reactions (which have resulted in death). Premedication with acetaminophen and diphenhydramine is common before the first dose of any antibody. If a severe reaction occurs, the infusion should be stopped and the patient treated with antihistamines, corticosteroids, or other supportive measures. [Pg.1294]

Maintenance toxoplasmosis 1 tab PO 3 times a v ek blood dyscrasias, allergic reactions. [Pg.65]

Detection of head lice infestation is based on identifying lice by detection combing. Head lice detection cannot be solely based on an itchy scalp because not all children with head lice have the symptom. Furthermore, itchiness is caused by an allergic reaction to the lice, which may develop a few weeks after the infection and can persist for some time after eradication. Infestation is equally likely to occur in clean or dirty hair. [Pg.37]

The chromone cromolyn sodium (5-5) was at one time considered the forerunner of a novel class of antiallergic and antiasthmatic drugs that act at one of the earliest stages of the allergic reaction. Detailed experiments, acmally conducted after the dmg s clinical effectiveness had been confirmed, suggested that the compound inhibited the release of mediators of the allergic reaction from mast cells. The dmg is not very active when taken orally and is usually applied topically to the lung by insufflation as its sodium salt. Considerable efforts to uncover additional structurally related mediator release inhibitors have had only limited success. [Pg.432]


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