Allergic alveolitis reaction

Malmberg P et al (1988) Incidence of organic dust toxic syndrome and allergic alveolitis in Swedish farmers. Int Arch Allergy Appl Immunol 87(l) 47-54 Malmberg P, Rask-Andersen A, Rosenhall L (1993) Exposure to microorganisms associated with allergic alveolitis and febrile reactions to mold dust in farmers. Chest 103(4) 1202-1209... 

Warren CP (1977) Extrinsic allergic alveolitis a disease commoner in non-smokers. Thorax 32(5) 567-569 Warren P, Cherniack RM, Tse KS (1974) Hypersensitivity reactions to grain dust. J Allergy Clin Immunol 53(3) 139-149 Warren CP, Tse KS, Cherniack RM (1978) Mechanical properties of the lung in extrinsic allergic alveolitis. Thorax 33 315-321... 

Evidence that a substance can induce specific respiratory hypersensitivity will normally be based on human experience. In this context, hypersensitivity is normally seen as asthma, but other hypersensitivity reactions such as rhinitis/conjunctivitis and alveolitis are also considered. The condition will have the clinical character of an allergic reaction. However, immunological mechanisms do not have to be demonstrated. 

Hemolytic anemia has been reported (SEDA-10, 79) (SEDA-12, 83). A high percentage of patients taking azapropazone had a positive direct Coombs test, but this did not persist after treatment had been stopped for several weeks (SEDA-12,83). Hemolytic anemia has also been described in combination with pulmonary alveolitis, which suggests an allergic or immune reaction (3). Photosensitivity is often reported 190 reports of photosensitivity were submitted to several national drugmonitoring centers in Europe in 1985 (SEDA-10, 79) (SEDA-12, 83). 

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