Allenylation of Pyrroles with 3- Trichloropropane

SCHEME 2.126 Synthesis of N-aUenylpyrroles from pyrroles and trichloropropane in KOH/DMSO system. 

In light of the availability of 1,2,3-trichloropropane, a large-scale waste of epi-chlorohydrin production, the simple and efficient method for pyrroles allenylation under mild conditions holds promise for further applications in the synthesis of various heterocyclic compounds with a labile hydrogen atom. 

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