Alginate stabilizing, gels

FDA testing and previous studies have verified that 150-250 cP is an ideal range for decreased sodium alginate injection resistance in many standard over-the-wire microcatheter systems and increased calcium alginate stability in gel form (Becker et al, 2005 2007). As for newer flow-directed microcatheter systems, an injectable biomaterial requires a lower alginate viscosity range (1-150 cP) to accommodate the microcather s minimal inner diameter. 

In this study, lipoxygenase was successfully entrapped by a novel immobilization method within a calcium-alginate silicate gel matrix. The entrapped lipoxygenase had stability better than LOX immobilized by other methods. The immobilized preparation also was reusable. This procedure should enhance the potential of LOX as a biocatalysts in the preparation of oxygenated fatty acid derivatives that have unique chemical and physical properties. 

The hydrocolloids used stabilize this type of icing by their ability to form a gel or a highly viscous solution. Agar-agar, locust bean gum, sodium alginate (combined with a buffer and calcium salt), Irish moss extract, pectin, and karaya gum are hydrocolloids used. The finished icing may contain from 0.1 to 0.5% hydrocolloids. 

There are also several water-soluble mixtures of polysaccharides, including those derived from seaweeds and marine animals, such as gum arabic, agar, algin, carrageenan, and chitin. These are hydrophilic. Their suspensions in water can be quite viscous and can readily form gels, and they can form viscous interfacial films around dispersed droplets and bubbles [821], They are used to stabilize suspensions, foams, and emulsions and are used in many different foods and medicines including, for example, ice cream [428,430], See also Ref. [822],... 

In topical formulations, sodium alginate is widely used as a thickening and suspending agent in a variety of pastes, creams, and gels, and as a stabilizing agent for oil-in-water emulsions. 

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