Ritonavir Alfuzosin

ALPHA-BLOCKERS PROTEASE INHIBITORS Possible T alfuzosin levels with ritonavir Uncertain Avoid co-administration... 

Clinically important, potentially hazardous interactions with alpha blockers (alfuzosin), doxazosin, erythromycin, fosamprenavir, indinavir, itraconazole, ketoconazole, nitrates, ritonavir, tamsulosin, terazosin... 

The US manufacturers of alfuzosin XL briefly cite a study in which keto-conazole 400 mg increased the AUC and maximum levels of a 10-mg dose of alfuzosin by 3.2-fold and 2.3-fold, respectively. They therefore contraindicate the concurrent use of potent CYP3A4 inhibitors (they name itraconazole, ketoconazole and ritonavir). ... 

---