Alcohol long-term health effects

C. The likelihood of gastric ulceration and GI bleeding is increased by heavy alcohol use, poor health, advanced age, long-term NS AID use, and use of drugs such as corticosteroids and anticoagulants. Ibuprofen is not converted to a cardiotoxic metabolite. Dermal toxicities, such as epidermal necrolysis, are rare complications of ibuprofen therapy, but necrotizing fasciitis is not one of them. Confusion and ataxia are not side effects associated with ibuprofen, nor is eosinophilia. 

There are very few adverse health effects as far as organ or tissue damage from long-term (years) use of codeine. This is in contrast to most other abused drugs, with alcohol and tobacco being the obvious examples. 

Inhalant abuse refers to the intentional inhalation of such products to experience a carefree, euphoric high. The exact mind-altering effects of inhalants vary, depending on the product involved, but they are generally similar to those produced by alcohol intoxication or anesthesia. The health ramifications can be serious, in both the short and long term, because most inhalants are highly toxic. 

Toxicity and health effects Vapors of amyl alcohol cause mild irritation to mucous membrane of the eyes, nose, throat, and upper respiratory tract and to the skin. Acute and long-term exposures to amyl alcohol cause nausea, vomiting, headache, vertigo, and muscular weakness. Prolonged exposure may also cause narcotic effects. - ... 

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