Alclofenac

C3H5S 870-23-5) see Altizide allyl(l-methyl-2-pentynyl)malonic acid diethyl ester (C16H24O4 101448-52-6) see Methohexital 4-allyloxy-3-chlorobenzaldehyde (CigH Cl02, 58236-91-2) see Alclofenac 4-allyloxy-3-chlorobenzyl chloride (C Hi()Cl20 20788-43-6) see Alclofenac 4-allyloxy-3-chlorobenzyl cyanide (C, H C1N0 20788-44-7) see Alclofenac... [Pg.2289]

CNNa 143-33-9) see Alclofenac Alpidem Amphetaminil Atorvastatin calcium Azatadine Calcium pantothenate Carnitine Clopidogrel hydrogensulfate Clortermine Dexrazoxane Diclofenac Diloxanide Edetic acid Epinastine hydrochloride Ethosuximide Ethotoin Fenoprofen Ibuprofen Irbesartan Ketoprofen Lonazolac Mephenytoin Mepindolol Montelukast sodium Nabilone Oxymetazoline Paramethadione Pentorex Saquinavir Suprofen Thiamphenicol Tolmetin Trimazosin Zolpidem sodium cyanoborohydride... [Pg.2441]

Suggest conditions for this synthesis of the analgesic alclofenac. [Pg.46]

Alclofenac (26) represents one of the more extreme simplifications in this class of antiinflammatory agents. The general method for prepara-... [Pg.68]

In contrast, a number of alkene epoxides (10.3) are chemically quite stable, i.e., intrinsically less reactive than arene oxides. Examples of epoxide metabolites that have proven to be stable enough to be isolated in the absence of degrading enzymes include 1,2-epoxyoctane (10.4), 1,2-epoxycyclohex-ane (10.5), 1-phenyl-1,2-epoxy ethane (styrene oxide, 10.6), and cis- 1,2-diphenyl-1,2-epoxyethane (cfv-stilbene oxide, 10.7) [12], The same is true of alclofenac epoxide (10.8), hexobarbital epoxide (10.9), and a few other epoxides of bioactive compounds. [Pg.611]

J. A. Slack, A. W. Ford-Hutchinson, M. Richold, B. C. K. Choi, Some Biochemical and Pharmacological Properties of an Epoxide Metabolite of Alclofenac , Chem.-Biol. Interact. 1981, 34, 95 - 107. [Pg.675]

Major drugs withdrawn between 1971 and 1982 for safety reasons included polidexide (introduced 1974 and withdrawn 1975), oral formulation of practolol (1970 and 1976), alclofenac (1972 and 1979), tienilic acid (1979 and 1980), clomacron (1977 and 1982) and indoprofen (1982 and 1982). [Pg.477]

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