Akebia

Akebia Announce Positive Results for AKB-6548 Phase 1 Clinical Study, January 5, 2010, http //www.akebia.com/AKB6548 Phase la Completion.pdf (accessed July 6, 2010). 

Akebia quinata (Hoytt.) Decne. Moo Tune (Chocolate vine) See Clematis armandii ... 

N.A. Akebia trifoliata (Thunb.) G. Koidz. No information is available in the literature. Control infection, stimulate the circulatory and urinary systems. Diuretic properties.345... 

Fujita, M., H. Itokawa, and Y. Kumekawa. 1974. The study on the constituents of Clematis and Akebia spp. I. Distribution of triterpenes and other components. Yakugaka Zasshi 94 189-191. 

Alkaloids are not known. Tests conducted in this study on Akebia longerucemosa, A. quinata, and Stauntonih hexaphyllu were negative. 

Aristolochia, Akebia, Clematis, Clematidis, Cocculus, Serpentaria, Stephania... 

Arjungenin (107) from Terminalia arjuna is the C-19 epimer of tomentosic acid/ A new nortriterpenoid, norarjunolic acid (108), has been isolated from Akebia quinata where it occurs with arjunolic acid. The structure of the ketol (109), from the stems of Castanopsis lamontii, was confirmed by its partial synthesis from 14a,15a-epoxytaraxeran-3-one (110). Other new oleananes include phytolac-... 

For damp heat in the lower burner with frequent urination, urgency, and pain, add Caulis Akebiae Mutong Mu Tong), Rhizoma Alismatis Ze Xie), and Semen Plantaginis Che Qian Zi). 

Raw Rehmannia cools the blood and enriches yin, thus restraining heart fire. Akebia clears heat from the heart channel above, while below, it also clears heat from the small intestine. In addition, it disinhibits water and opens strangury. Raw Licorice clears heat and resolves toxins and regulates and harmonizes the other medicinals. In particular, it is believed that using Licorice s small root tips stops strangury and pain. Bamboo Leaves clear the heart and eliminate vexation. 

Radix Angelicae Sinensis (Dang Gui), 12g Ramulus Cinnamomi (Gui Zhi), 9g, remove the skin Radix Paeoniae Lactiflorae (Shao Yao), 9g Herba Cum Radice Asari (Xi Xin), 1.5g Radix Glycyrrhizae (Gan Cao), 5g, mix-fried Caulis Akebiae Mutong (Mu Tong), 3g Fructus Zizyphi Jujubae (Da Zao), 8 pieces... 

Within this formula, Dang Gui is bitter, acrid, sweet, and warm. It supplements and harmonizes the blood. Combined with Peony, these two supplement blood vacuity and are the sovereign medicinals in this formula. Cinnamon is acrid, sweet, and warm. It warms the channels and scatters cold. Combined with Asarum, these two scatter cold from both the inside and outside. They are the minister medicinals in this formula. Licorice and Red Dates are sweet. They boost the qi and fortify the spleen. In addition, they help Dang Gui and Peony supplement the blood and Asarum and Cinnamon open yang. Licorice and Red Dates are the assistant medicinals. Further, Akebia opens the channels and vessels. It is the messenger medicinal in this formula. Once blood vacuity is remedied and yang qi is restored, the hands and feet become warm automatically. 

For dysmenorrhea due to blood vacuity with cold evils, subtract Akebia and add prepared Radix Rehmanniae Shu Di) to nourish the blood and regulate menstruation. 

For painful urinary strangury in the elderly due to fallen yang qi, add Rhizoma Alismatis ZeXie) and Caulis Akebiae Mutong Mu Tong). 

In this formula, Akebia, Talcum, Plantaginis, Dianthus, and Polygonum Avicularis all disinhibit water and open strangury. They also clear heat and disinhibit dampness. Gardenia clears and drains damp heat from the three burners. Rhubarb discharges heat and downbears fire. Juncus conducts heat and moves it downward. Licorice harmonizes these medicinals and relaxes urgency or tension. 

For urinary retention, increase the dosage of Talcum, Polygonum Avicularis, and Akebia and add Cortex Phellodendri Huang Bai) and Cortex Cinnamomi Rou Gui). 

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