Affinity chromatography carbohydrate specificity determination

Sugar moieties on glycoproteins Protein-carbohydrate complexes identification and mimicking of key residues determining monosaccharide specificity Solid-phase combinatorial chemistry (80 ligands) Affinity chromatography 1H-NMR studies 8,16,17... [Pg.46]

In this article, we have described several uses of carbohydrate compounds as affinity ligands. These few examples clearly demonstrate the importance of such affinity supports in the separation of biological products. Affinity chromatography is also able to help in the determination of the interaction mechanisms of carbohydrate derivatives in biological reactions. This developing field of research will lead to improved quality and specificity of affinity-chromatographic phases. [Pg.302]