Advances in the Applications of Controlled Delivery Systems and Clinical Relevance

3 Advances in the Applications of Controlled Delivery Systems and Clinical Relevance 

PEG-based copolyesters possess the ability to serve as absorbable controlled release carriers for a whole host of bioactive agents. The ability to provide a means of local therapy with systemically toxic agents directly at the site of interest has heightened awareness of these PEG-based systems. In addition, since these copolymers are absorbable, they allow for local drug delivery without the inherent risks associated with permanent foreign bodies. Some applications of the PEG-based systems include, but are not limited to, antibiotic formulations for osteomyelitis, controlled release of vaccines, intra-vaginal delivery of misoprostol, periodontal application of antibiotics, and intraocular drug delivery. 

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