Adsorption unmodified cellulose

Adsorption systems are governed by adsorption rather than a partition mechanism. Compounds adsorbed by cellulose may be separated on unmodified cellulose developed with water or salt solutions [33]. Compounds adsorbed by adsorbents such as silica or alumina are separated on papers impregnated with these adsorbents and developed with organic solvents. 

FTIR spectroscopy has proven to be particularly useful in gaining an understanding of the biocompatibility phenomenon. It is believed [746, 841, 856, 857] that protein adsorption is the initial step in the interaction of blood with implanted biomaterials, followed by adhesion of cells and subsequent tissue attachment. This implies that the substrate surface characteristics influence the process, which was confirmed by ATR studies of albumin adsorption on calcium phosphate bioceramics and titanium [763] and segmented polyurethane [764], albumin and fibrinogen on acetylated and unmodified cellulose [765, 766], poly(acrylic acid)-mucin bioadhesion [767], polyurethane-blood contact surfaces [768], and other proteins on poly(ester)urethane [769], polystyrene [767, 771] and poly(octadecyl methacrylate) [771] and by IRRAS study of adsorption of proteins on Cu [858]. Another branch of IR spectroscopic studies of protein adsorption relates to microbial adhesion (Section 7.8.3). 

I Cellulose as Adsorbent Unmodified cellulose has a low adsorption capacity to metal ions as well as variable physical stabihty. Cellulose is not only renewable, biodegradable, and inexpensive, but also has many primary active hydroxyls (Fig. 5.2) which are easy to trigger many reactions, such as free radical reaction, esterification, halogenation, oxidation, and etherification [62], Various kinds of cellulose derivatives are synthesized by these reactions. Therefore, chemical... 

Much work has been done with polymers to create biocompatible surfaces that resist protein fouling, i.e., non specific adsorption. A membrane composed of modified polyethersulfone (PES) (Omega Membrane) resisted albumin (ALB) absorption 24 times better than unmodified PES, and three times better than regenerated cellulose, a material known to resist biofouling. We compared porous SiC, both n-type and p-type, to the Omega Membrane [14] and found a very similar resistance to ALB absorption (Figure 12.3). 

---