Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Adenoviruses, tissue-specific

Not only by crossing with mice which egress Cre, but also by infection with Cre-adenovirus vectors the tissue-specific control of the knockout event can be achieved. This is a simple and attractive approach which reduces time, labour, and the number of animals needed for breeding. Adenoviral delivery of Cre in adult ventricular cardiomy-ocytes in vivo has been shown effective. ... [Pg.381]

Doronin K, Kuppuswamy M, Toth K, Tollefson AE, Krajcsi P, Krougliak V, Wold WS. Tissue-specific, tumor-selective, replication-competent adenovirus vector for cancer gene therapy. J Virol 2001 75(7) 3314-3324. [Pg.167]

The second delivery method, called in mvo, means that the virus is used to directly infect the patient s tissues. The most common vector for this delivery is the adenoviras (which is a DNA virus). A particular vector can be chosen based on specific receptors on the target tissue. Adenovirus has receptors in lung and liver cells, and it has been used in clinical trials for gene therapy of cystic fibrosis and ornithine transcarbamoylase deficiency. [Pg.412]

See other pages where Adenoviruses, tissue-specific is mentioned: [Pg.273]    [Pg.249]    [Pg.983]    [Pg.948]    [Pg.952]    [Pg.1129]    [Pg.178]    [Pg.66]    [Pg.2]    [Pg.329]    [Pg.230]    [Pg.231]    [Pg.79]    [Pg.266]    [Pg.145]    [Pg.484]    [Pg.426]    [Pg.155]    [Pg.165]    [Pg.165]    [Pg.1954]    [Pg.261]    [Pg.167]    [Pg.1267]    [Pg.160]    [Pg.616]    [Pg.298]    [Pg.358]    [Pg.240]    [Pg.616]    [Pg.509]    [Pg.17]    [Pg.160]   


SEARCH



Gene therapy vectors, tissue-specific adenovirus

Tissue specificity

Tissue-specific

© 2024 chempedia.info