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Acute toxicity guideline documents

The guidance document offers a comparison of TG 420 (Fixed Dose Method), TG 423 (Acute Toxic Class Method), and TG 425 (Up-and-Down Procedure). The purpose of this Guidance Document is to provide information to assist with the choice of the most appropriate Guideline to enable particular data requirements to be met while reducing the number of animals used and animal suffering. The Guidance Document also contains additional information on the conduct and interpretation of test guidelines 420, 423, and 425. [Pg.110]

See other pages where Acute toxicity guideline documents is mentioned: [Pg.174]    [Pg.205]    [Pg.20]    [Pg.27]    [Pg.734]    [Pg.102]    [Pg.104]    [Pg.52]    [Pg.2505]    [Pg.38]    [Pg.48]    [Pg.4]   
See also in sourсe #XX -- [ Pg.110 ]



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