Acute lymphoblastic leukemia , survival

Efferth et al. (155) Acute lymphoblastic leukemia 53 patients Overall survival No statistical difference... 

Thiopurines (mercaptopurine, thioguanine, and azathioprine) are important anticancer and anti-inflammatory medications. The use of thiopurines in combination chemotherapy has increased the survival rates of children with acute lymphoblastic leukemia from less than 10% 40 years ago to more than 80% today (20). However, interindividual variation in toleration of... 

Paradoxically, this high prevalence of children with special health care needs is related to advances in medical science, which have greatly increased survival rates for a number of health conditions. For example, the median survival age for children with cystic fibrosis has more than doubled in the last 3 decades, up fi om 11 years in 1966 to 29 years in 1993 (Cystic Fibrosis Foundation, 1994). Similarly, acute lymphoblastic leukemia (all), a disease that was once almost uniformly fatal, now has an average childhood survival rate of 5 years or more (Mulhern ... 

Carcinogenesis. Surviving victims of mustard exposure during the Iran-haq War are exhibiting carcinoma of the nasopharynx, bronchogenic carcinoma, adenocarcinoma of the stomach, as well as acute myeloblastic and lymphoblastic leukemia (Balali-Mood and Hefazi, 2006). Definitive studies of the nature and types of cancers seen in this patient population and correlations with severity of exposure have yet to be published. 

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