Acute Effects on Animals

Acute Effects on Animals and Humans Due to the poor solubility of thorium and the low radiotoxicity of natural thorium, no acute effects on humans are reported. Cases of severe pneumoconiosis have been described in photoengravers working with rare earth elements/thorium electrodes. 

Acute Effects on Animals and Humans Eor humans and animals, uranium and its salts are highly chemotoxic. Dermatitis, renal damage and acute arterial lesions may occur. Uranyl compounds readily com-... 

Acute Effects on Animals and Humans Only radiotoxicity has to be considered for Pu and shorter-lived actinides. See the corresponding text for uranium (Chapter 26.2, Section 26.2.6.1) for details. 

Studies of effects on animals following acute, intermediate, and chronic dermal exposure to marine diesel fuel and JP-5 fuel provide evidence for dermal absorption (NTP/NIH 1986). Case reports concerning a man who washed his hair with an unknown amount of diesel fuel (Barrientos et al. 1977) and a man who washed his hands with an unspecified diesel fuel over several weeks (Crisp et al. 1979) provide possible evidence for dermal absorption, but effects resulting from inhalation versus dermal exposure could not be distinguished in these cases. No other data on the absorption of fuel oils following dermal exposure in humans or animals were located. 

PS Is acutely toxic, with a variety of effects on animals. 

Acute-Duration Exposure. There are reports on the health effects resulting from acute exposure of humans and animals to benzene via the inhalation, oral, and dermal routes. The primary target organs for acute exposure are the hematopoietic system, nervous system, and immune system. Acute effects on the nervous system and immune system are discussed below under Neurotoxicity and Immunotoxicity. Information is also available for levels that cause death in humans (e.g., Cronin 1924 ... 

The question of occasional long-lasting or late-appeaiittg residual effects Is not easily answered. There is very little evidence chat these might occur In man. In that so many persons have been exposed to these agents. The new case of glomerulltis several years after exposure In all likelihood was coincidental. Animal studies have been equivocal, but they have suggested Che possibility of acute effects on the kidney and liver In some Instances. 

Acute effects in animals and humans resulting from a cesium deficiency or related to high cesium intake have not been reported. A high intake of cesium is rapidly excreted via the kidneys (Yamagata etal., 1966), and consequently no reports have been made on any chronic effects due to stable cesium intake. Neither have any mutagenic, carcinogenic or teratogenic effects of stable cesium been either studied or described. 

Toxicology Exposure is by ingestion. It bas a low acute toxicity, and the lARC say that there is limited evidence for its carcinogenic effect on animals. 

What effects does it have on humans and other animals Well, the acute effects on humans (e.g., workers in the DDT-manufacturing plants) are not lethal. It gives headache and fatigue. In an eagerness to promote the DDT s usefulness, some advocates demonstrated its non-toxicity by drinking a cocktail of DDT. The effect was slight. DDT, however, is chemically toxic for human just as for flies and worms, but the differences in body size and physiology make the toxic effects of DDT appear different. We will talk about subtler and, perhaps, more serious effects of DDT later. 

It has slight short-term toxicity on aquatic life. Acetone has caused membrane damage, a decrease in size and a decrease in germination of various agricultural and ornamental plants. It may also have slight longterm toxicity to aquatic life. Chronic and acute effects on birds or land animals have not been determined. 

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