Acholuric jaundice

Gunn, C.K. (1938). Hereditary acholuric jaundice. 1. Hered. 20 137-145 Hamer, R.D., Dobson, V, and Mayer, M.J. (1984). Absolute thresholds in human infants exposed to continuous fllumination. Invest. Ophthalmol. 6s. Sci. 25 381-388 Hanefeld, F. and Natzschka, J. (1971). Histochemical studies in infant Gunn rats with kemicterus. Neuropediatrie 2 428-438... 

Gunn, C. H. (1938). Hereditary Acholuric Jaundice in a new mutant strain of rats. J Hered 29, 137-139. 

The commonest causes of obstructive (posthepatic) jaundice are cancer of the head of the pancreas and a gallstone lodged in the common bile duct. The presence of bilirubin in the urine is sometimes referred to as choluria—therefore, hepatitis and obstruction of the common bile duct cause choluric Jaundice, whereas the Jaundice of hemolytic anemia is referred to as acholuric. The laboratory results in patients with hepatitis are variable, depending on the extent of damage to parenchymal cells and the extent of micro-obstruction to bile ductules. Serum levels of ALT and AST are usually markedly elevated in hepatitis, whereas serum levels of alkaline phosphatase are elevated in obstructive liver disease. 

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