4-acetylphenyl methyl

A Baker-Venkataraman rearrangement of 2-acetylphenyl methyl phthalate 753 forms the (3-diketone intermediate 754, which undergoes successive ring closures leading to the formation of benzo[ ]indeno[2.1-< ]pyran-l-,ll-dione 755 in high yield (Scheme 195) <2002TL4515>. 

Methyl 2-(3 -Phenyl-2 -propen-r-oyl)phenyl Tellurium3 A stirred mixture of 12 g (46 mmol) of 2-acetylphenyl methyl tellurium, 17.6 m/(18.4 g, 170 mmol) of benzaldehyde, 88 mlof acetic acid, and 35 ml of piperidine is heated under reflux for 6 h. The mixture is then steam-distilled to remove unreacted benzaldehyde. The resultant red oil is separated by extraction with chloroform, the extract is evaporated, and the residue is fractionally distilled under vacuum. The fraction boiling above 200°/0.1 torr is collected and redistilled to give a condensate that should solidify. This solid is recrystallized several times from a mixture of petroleum ether and benzene yield 3.2 g (20%) m.p. 102-104° (from heptane/benzenc). 

The acetyl-methyl group in 2-acetylphenyl methyl tellurium condenses with benzaldehyde to give methyl 2-(3 -phenyl-2 -propen-l -oyl)phenyl tellurium. ... 

Finally, the bacterial PTE mentioned above has also been exhaustively studied with regard to its enantioselectivity. Initial studies used the known crystal structure of PTE to identify the substrate-binding pocket. This was then rationally evolved for enhancement and relaxation of the stereospecificity.97 Most recently, a combinatorial library has been screened for the resolution of chiral phosphate, phosphonate, and phosphinate esters.124 This work identified two variants with markedly different preferences for 5p- and Rp-enantiomers of 4-acetylphenyl methyl phenyl phosphate. One variant preferentially catalyzed hydrolysis of the 5p-enantiomer by a factor of 3.7 x 105, while the other preferentially catalyzed hydrolysis of the A p-enantiomer by a factor of 9.7 x 102 - an enantioselective discrimination of 3.6 x 108. 

IsopropyI-4-nitrophenyl 2, 4-nitrophenyl 3, 2-methyl-3-nitrophenyl 4, 2-methyl-4-nitrophenyl 5, 3-fluorenyl 6, 1-fluorenyl 7, 2,6-dimethyl-4-nitrophenyl 8, 3-benzoyl-phenyl 9,4-benzoylphenyl 10,9-anthracenyl 11, 3-acetylphenyl 12,4-acetylphenyl 13, 1-naphthyl. 

Acetylphenyl butyl tellurium is formylated at the acetyl-methyl group by methyl formate and sodium in diethyl ether. The formyl compound is converted to butyl 2-(diazoacetyl)-phenyl tellurium upon treatment with 4-methylbenzenesulfonyl azide1. The diazoacetyl group is converted to the dibromoacetyl group by bromine in diethyl ether1. 

Methyl-1-phenyl-1,5-hexadiene was obtained in a similar manner as 3-(4-acetylphenyl)- -butene depicted in 2.4.1. 

Kinetic studies on the basic hydrolysis of / -acetylphenyl 3- and 5-0-methyl->-D-xylofuranoside were reported by H. Lonnberg, Finn. Chem. Lett. 1978, 213 and support the idea of greater base-lability of trans-O-furanosides. 

Hydrolyses of the glycosidic linkages of phenyl a- and 3-D-glucopyranoside were studied at different alkali concentrations, and the reaction rates increased rapidly above 2M. Mechanisms involving direct hydrolysis and the intermediacy of l,6-anhydro- 8-D-glucose and, with the j3-anomer, the l,2-a-anhydride were proposed. Analogous work with p-acetylphenyl 3- and 5-0-methyl- 3-D-xylo-furanoside led to the conclusion that the 2-oxyanions (and presumably 1,2-anhydrides) were involved as intermediates. ... 

IV-Phenylimidazolium triflate IV-Phenylimidazolium perchlorate 2-(Bromo)-4,5-(dicyano)imidazole IV-Methylbenzimidazolium triflate Pyridinium tetrafluoroborate IV-Methylanilinium trifluoroacetate lV-(p-Acetylphenyl)imidazolium triflate IV-Phenylimidazolium tetrafluoroborate ImidazoUum perchlorate 5-(/t-Nitrophenyl)-l//-tetrazole 4,5- (Dicy ano)imidazDle 4-(Phenyl)imidazDlium triflate Benzimidazolium tetrafluoroborate Imidazolium tetrafluoroborate Imidazolium triflate Benzimidazolium triflate 2-(Phenyl)imidazolium triflate A-Methylimidazolium triflate 4-(Methyl)imidazolium triflate l//-Tetrazole... 

Poly(l-phenylethylene) Polystyrene -[C HgCHCHJ Poly[l-(4-acetylphenyl)ethylene] Poly[l-(4-benzoylphenyl)ethylene] Poly[l-(4-bromophenyl)ethylene] Poly[l-(4-butoxyphenyl)ethylene] Poly[l-(4-butoxycarbonylphenyl)ethylene] Pol[(l-(4-butylphenyl)ethylene] Poly[l-(4-carboxyphenyl)ethylene] Poly[l-(2-chlorophenyl)ethylene] Poly[l-(3-chlorophenyl)ethylene] Poly[l-(4-chlorophenyl)ethylene] Poly[l-(2,4-dichlorophenyl)ethylene] Poly[l-(2,5-dichlorophenyl)ethylene] Poly[l-(2,6-dichlorophenyl)ethylene] Poly[l-(3,4-dichlorophenyl)ethylene] Poly[l-(2,4-dimethylphenyl)ethylene] Poly[l-(4-(dimethylamino)phenyl)ethylene] Poly[l-(4-ethoxyphenyl)ethylene] Poly[l-(4-ethoxycarbonylphenyl)ethylene] Poly[l-(4-fluorophenyl)ethylene] Poly[l-(4-iodophenyl)ethylene] Poly[l-(4-methoxyphenyl)ethylene] Poly[l-(4-methoxycarbonylphenyl)ethylene] Poly(l-methyl-l-phenylethylene)... 

Rivastigmine co-TA Paracoccus denitrificans) 3-Acetylphenyl ethyl(methyl)carbamate+L-alanine AS [39]... 

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