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Acetylferrocene, reaction with

Poly(ethynylferrocene) (3) involving a polyacetylenic backbone was synthesized by heating ethynylferrocene with initiators such as benzoyl peroxide [122,123] or AIBN [124], with a Ziegler catalyst, AlEt3-Ti(OBu)4 [125] or AlBu -TiCU [126], and by polycondensation of acetylferrocene in molten, anhydrous ZnCl2 [127] or by reaction with calcium carbide or ammonium carbonate [128]. The latter method using acetylferro-... [Pg.815]

Friedel-Crafts acylation involves electrophilic attack by acyl cation (CHsCO ) on the ring, and the ring s electronic character should indicate its susceptibility to attack. Compare electrostatic potential maps of ferrocene and acetylferrocene. Which molecule contains the most electron-rich ring Which acylation reaction should be faster Does an acetyl substituent enhance or diminish ring reactivity What should be the major product when ferrocene is combined with one equivalent of acetic anhydride ... [Pg.194]

Hydrazones are also useful substrates in the preparation of pyrazoles. Reaction of N-monosubstituted hydrazones with nitroolefins led to a regioselective synthesis of substituted pyrazoles <060L3505>. lf/-3-Ferrocenyl-l-phenylpyrazole-4-carboxaldehyde was achieved by condensation of acetylferrocene with phenylhydrazine followed by intramolecular cyclization of the hydrazone obtained under Vilsmeier-Haack conditions <06SL2581>. A one-pot synthesis of oxime derivatives of l-phenyl-3-arylpyrazole-4-carboxaldehydes has been accomplished by the Vilsmeier-Haack reaction of acetophenone phenylhydrazones <06SC3479>. [Pg.210]

Acylmetallocenes undergo many reactions shown by acylbenzenes (35, 87, 91, 116, 124), but a detailed discussion is not presented here. Reductions with either lithium aluminum hydride or sodium borohydride give the corresponding carbinols, while Clemmensen reduction, reduction with lithium aluminum hydride plus aluminum chloride, catalytic hydrogenation, etc., yield corresponding alkyl derivatives. Acetylferrocenes undergo a variety of base condensation reactions and can be oxidized to ferrocenecarboxylic acids without apparent oxidation of the iron atom. [Pg.66]

Analyze your product by thin-layer chromatography. Dissolve very small samples of pure ferrocene, the crude reaction mixture, and recrystallized acetylferrocene, each in a few drops of toluene spot the three solutions with microcapillaries on silica gel plates and develop the chromatogram with 30 1 toluene-absolute ethanol. Visualize the spots under a uv lamp if the silica gel has a fluorescent indicator or by adsorption of iodine vapor. Do you detect unreacted ferrocene in the reaction mixture and/or a spot that might be attributed to diacetylferrocene ... [Pg.364]

The reactions of Cp2TiCl2 with a class of organometallic thiosemicarbazones (LH), derived by condensing acetylferrocene with substituted thiosemicarbazides or with Schiff bases (L), derived by the condensation of acetylferrocene with ethylenediamine, 0-phenylenediamine, 4-methyl-o-phenylenediamine, 1,8-diaminonaphtha-lene, and 2,6-diaminopyridine, have been studied to give a type of bimetallic products Cp2TiClFe(L). Attempts... [Pg.586]

The potential use of Cp2TiCl2 in the treatment of neoplasia has been reported.2022 The reaction of Cp2TiCl2 with phosphorus- and sulfur-based [3-amino acid analogs under atmospheric conditions has also been described.2023 The reactions of Cp2TiCl2 with organometallic acetylferrocene thiosemicarbazones to give bimetallic products have been reported. Physicochemical and spectral studies have been carried out in order to establish a correlation between the biological activity and the structures of the compounds.1525... [Pg.664]

The study of the chemistry of acyl groups other than formyl is much less developed. Acetyltetrathiafulvalene (63) has been subjected to crossed aldol condensations with acetylferrocene and (acetophenone) Cr(CO)3 [92JOM(429)335]. Some Wittig reactions of 63 have been reported (93TL7475), as well as a few reactions of ketone 64 (90CC816) (Scheme 27). [Pg.261]

Method II, The Meerwein-Ponndorf-Verley reaction A solution of 3 g of acetylferrocene in 300 mL of isopropyl alcohol was passed through a tube of diameter 25 mm and length 700 mm filled with activated AI2O3 for 3 h at a pressure of 900 to 1300 Pa and 200-210 °C. From the condensate 2.3 g of vinylferrocene was isolated and chromatographed via a column with AI2O3, hexane was used as the eluent. After evaporation of the solvent, 1.95 g of the metallomonomer was obtained (70% of the yield). [Pg.162]

Sasaki, Yu. and Pittman, Ch. U., Jr. Acid-Catalyzed Reaction of Acetylferrocene with Tri-etyl Orthoformate. J.Org.Chem., 38(21), 3723-3726 (1973). [Pg.87]

A polyamino carbonyl ferrocene dmivative formed by coupling ferrocene carboxylic acid with a BOC protected polyamine is claimed to be a mammalian excitatory neurotransmitter antagonist. Ferrocenyltetrazolylhydrozones have been prqrared from the condensation reaction of ferrocenecarboxaldehyde with a series of tetrazolylhydrazines. The reaction of ferrocoie carboxaldehyde with CH2(COR)(COR ), R = Me, R = Me, OEt in ether containing a Lewis base results in the formation of FcCH=C(COR)COR (mixture of E and Z isomers the work is extendable to diferrocenyl derivatives. Further work on the reduction of fluorine substituted methyl acetylferrocenes has been reported. "... [Pg.410]

The high reactivity of ferrocene in acetylation has been confirmed in a competitive reaction between ferrocene and anisole. When ferrocene and anisole were allowed to compete for a limited amount of acetyl chloride and aluminum chloride, acetylferrocene was formed to the exclusion of any detectable amount of methoxyacetophenone. Furthermore, ferrocene undergoes acetylation with acetic anhydride and stannic chloride or boron trifluoride even under mild conditions. [Pg.121]

A buffered ionic liquid is one in which the neutrality is maintained by reaction of excess alkali metal chloride when acid AICI3 is added. The latent acidity of this neutral system becomes observable when a weak base (B) such as A/,A/-dimethylaniline, pyrrole, or acetylferrocene is added.Reaction between the added base and the AICI3 results in adduct formation with precipitation of the alkali chloride MCI (Eq 2.29). [Pg.76]


See other pages where Acetylferrocene, reaction with is mentioned: [Pg.185]    [Pg.86]    [Pg.335]    [Pg.186]    [Pg.184]    [Pg.451]    [Pg.283]    [Pg.21]    [Pg.164]    [Pg.262]    [Pg.504]    [Pg.205]    [Pg.284]    [Pg.631]    [Pg.64]    [Pg.132]    [Pg.504]    [Pg.21]    [Pg.39]    [Pg.196]    [Pg.73]    [Pg.425]    [Pg.338]    [Pg.29]    [Pg.444]   


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Acetylferrocene

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