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Ticlopidine Acenocoumarol

Sotalol, metoprolol, propranolol, carvedilol, nifedipine, captopril, cilazapril, milrinone, ticlopidine, acenocoumarol, furosemide, acetylsalicylic acid, salicylic acid, ibuprofen, naproxen, ketoprofen, diclofenac, paracetamol, dipyrone, mildronate, sildenafil, dexa-methasone, carbamazepine, terbinafine/urine UHPLC MS/MS Column Zorbax Rapid Resolution High Definition SB-C18 (50 x 2.1 mm, 1.8 pm) Mobile phase Solvent A 0.1 % HCOOH in water Solvent B MeOH (gradient elution) Detection MS/MS, ionization ESI Protein precipitation LOQ 0.05-0.60 ng/mL [71]... [Pg.271]

Enalapril, paracetamol, sotalol, dipyrone, vancomycin, captopril, fluconazole, cefazolin, metoprolol, aspirin, ticlopidine, prednisolone, propranolol, digoxin, sildenafil, furosemide, dexamethasone, carvedilol, ketoprofen, nifedipine, terbinafine, acenocoumarol, spironolactone/urine HPLC DAD Column LiChroCART Purospher STAR, RP-18e (250 x 4 mm, 5 pm) Mobile phase MeOH ACN 0.05 % TFA in water (gradient elution) Detection DAD X = 200 50 nm Adjusted to pH 7.0, protein precipitation LOD 0.01-1.44 pg/mL LOQ 0.04-4.35 pg/mL [72]... [Pg.272]

Interfering acenocoumarol, alminoprofen, amodiaquine, benazepril, benperidol, chloro-quine, cicletanine, cocaine, dipyridamole, do o lamine, droperidol, hydroxychloroquine, ke-toprofen, labetalol, meperidine, mepivacaine, mexiletine, moclobemide, nomifensine, pi-pamperone, pyrimethamine, secobarbital, temazepam, ticlopidine, trazodone, viloxazine, vincristine, vindesine, zolpidem... [Pg.1373]

Interfering acenocoumarol, benazepril, bupivacaine, buprenorphine, buspirone, carbinox-amine, chlordiazepoxide, clorazepate, dipsrridamole, fenfluramine, flecainide, metapra-mine, metipranolol, mexiletine, midazolam, naproxen, oxprenolol, phencyclidine, pipam-perone, pyrimethamine, thiopental, tianeptine, ticlopidine, trazodone, triprolidine, verapamil, vincristine, vindesine... [Pg.1467]

In a retrospective analysis, the anticoagulant effects of acenocoumarol were modestly reduced by ticlopidine in 80% of patients, whereas, in a small prospective study, the anticoagulant effects of warfarin were unchanged by ticlopidine. As with other antiplatelet drugs, combined use might possibly increase bleeding risk. Cholestatic hepatitis has been reported in some patients given warfarin and ticlopidine. [Pg.384]

A retrospective study of 36 patients with heart valve prostheses found that when they took ticlopidine 250 mg daily, 29 of them needed a mean 13% increase in acenocoumarol dosage from 15.5 to 17.5 mg weekly, accompanied by a small DSTR rise from 3.05 to 3.13. One patient needed a dosage increase from 14 to 22 mg weekly. DSTR changes were detectable with a week of starting the ticlopidine. ... [Pg.384]

It seems possible that ticlopidine inhibits the metabolism of R-warfarin, but the interaction with acenocoumarol is not understood. Ticlopidine alone can cause raised liver enzymes and cholestatic hepatitis, and whether these cases represent an interaction is unclear. [Pg.384]

Salar A,DomenechP, Martinez F. Ticlopidine antagonizes acenocoumarol treatment. Thromb Haemost( 991) 11, 223-4. [Pg.384]

See other pages where Ticlopidine Acenocoumarol is mentioned: [Pg.60]    [Pg.124]    [Pg.228]    [Pg.384]    [Pg.403]    [Pg.489]    [Pg.622]    [Pg.745]    [Pg.801]    [Pg.845]    [Pg.888]    [Pg.933]    [Pg.1002]    [Pg.1142]    [Pg.1210]    [Pg.1450]    [Pg.384]    [Pg.228]    [Pg.384]    [Pg.489]    [Pg.622]    [Pg.745]    [Pg.801]    [Pg.845]    [Pg.888]    [Pg.933]    [Pg.1002]    [Pg.1142]    [Pg.1210]    [Pg.1450]   
See also in sourсe #XX -- [ Pg.384 ]



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Acenocoumarol

Acenocoumarole

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