Acarbose Acetaminophen

Clinically important, potentially hazardous interactions with acarbose, acetaminophen, alcohol, anticholinergic agents, atropine, miglitol... 

Neomycin may increase the efficacy and the gastrointestinal adverse effects of acarbose. There is some indirect evidence that acarbose with alcohol may increase the hepatotoxicity of paracetamol (acetaminophen). Parafytic ileus has been reported in a Japanese patient treated with acarbose and promethazine, an an-timuscarinic drug. 

Wang P-Y, Kaneko T, Wang Y, Sato A. Acarbose alone or in combination witii etiianol potentiates the hepatotoxicity of carbon tetrachloride and acetaminophen in rats. Hepatology (1999) 29, 161-5. 

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See also in sourсe #XX -- [ ]

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