Abscisic biosynthesis inhibitor

Abscisic Acid Biosynthesis Inhibitors Targeting 9-cis-Epoxycarotenoid Dioxygenase (NCED)... 

Chemical Genetics, Brassinosteroids, Biosynthesis, Inhibitors, Abscisic Acid, Carotenoid Cleavage Dioxygenase, Nine-cis-carotenoid Dioxygenase, Chemical Biology... 

Other Bioregulators. It should be mentioned that the physiological ly differently acting phytohormones abscisic acid cuid indolylacetic acid, which have different physiological activity, generate response patterns which exhibit little similarity either to each other or to those of the GA biosynthesis inhibitors. 

Miller, G. W., Sasse, J. M., Lovelace, C. J. and Rowan, K. S., 1984. Effects of podolactone-type inhibitors and abscisic acid on chlorophyll biosynthesis in barley leaves. Plant Cell Physiol. 25, 635-642... 

Plant products have also been detected in non-plant organisms. Morphine 1, the archetypal plant alkaloid, has in fact been shown to be a physiological plasma constituent and its production in mammals could be traced to the liver expression of the critical enzymes of its biosynthesis.17 In addition, the plant hormone abscisic acid 12 has been detected as an endogenous constituent of human brain,18 while caffeine 13 was isolated from a marine gorgonian (Paramuricea chamaelon)19 and the atisane diterpenoid serofendic acid 14, an inhibitor of the oxidant-induced mitochondrial death pathway and putative activator of mitoK(ATP) channels, has been characterised from foetal calf serum.20... 

C 5H2203, Mr 250.34, cryst., mp. 85 - 86 °C, [alp - 56° (CHCI3), a cyclofamesane sesquiterpene formed by photochemical oxidation of violaxanthin. It has been detected in several marine and higher plants. Naturally occurring X. exists as a mixture of -isomers of the 2,3-double bond of the 2,4-pentadienal side chain. It is an inhibitor of plant growth and is involved in the winter rest phase of plants (senescence), in some cases it is also involved in the damage to trees X. is closely related structurally and in its biological activity to abscisic acid and presumably functions as an intermediate in the biosynthesis of it. 

Thus, cell enlargement, for instance, depends upon auxin and involves the uptake of water, extension of the cell membrane and protein synthesis. The auxin dose-response curve consists of two peirts promotion by low concentrations and inhibition by higher concentrations via the formation of ethylene. Cytokinins and abscisic acid may possibly induce also, under special conditions, the production of ethylene. Many publications deal with effects of these plant hormones, especially of auxin, on ethylene biosynthesis in plants which occurs after a lag phase of 30 - 60 minutes and is specifically blocked by rhizobitoxin as well as by inhibitors of ENA and protein synthesis indicating that a continuous synthesis of protein is required for high rate of ethylene production (Eef. 20). 

In an indirect manner, the lipoxygenase reaction in higher plants appears to be implicated in the biosynthesis of abscisic acid, a further senescence hormone [23-25], Abscisic acid is formed from the carotenoid violaxanthin that is converted into xanthoxin, which is a plant growth inhibitor and at the same time a precursor of abscisic acid. The formation of xanthoxin requires the co-oxidative activity of a lipoxygenase-linoleic (or a-linolenic) acid system. 

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