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ABCG transporters

Sarkadi B, Homolya L, Szakacs G et al (2006) Human multidrag resistance ABCB and ABCG transporters participation in a chemoimmunity defense system. Physiol Rev 86 1179-1236... [Pg.752]

BCRP is classified in ABCG subfamily other members of this subfamily are involved in sterol transport (269). Unlike P-gp and MRPs, BCRP consists of a single ABC cassette in the amino terminal followed by six putative transmembrane domains however, it forms a homodimer linked by a disulfide bond in the plasma membrane (270,271). Initially, ABCG2 was identified as an mRNA expressed in placenta (272) and as a non-MDRl- and non-MRP-type resistance factor from cell lines selected in the presence of anthracy-clines and mitoxantrone (273). BCRP is expressed widely in the normal tissues (274) and localized on the canalicular membrane of the hepatocytes and apical membranes of epithelial cells (274,275) and brain capillary endothelial cells (276,277). [Pg.167]

See other pages where ABCG transporters is mentioned: [Pg.66]    [Pg.276]    [Pg.66]    [Pg.276]    [Pg.4]    [Pg.749]    [Pg.749]    [Pg.1158]    [Pg.322]    [Pg.267]    [Pg.267]    [Pg.268]    [Pg.341]    [Pg.582]    [Pg.279]    [Pg.204]    [Pg.4]    [Pg.749]    [Pg.749]    [Pg.1158]    [Pg.278]    [Pg.394]    [Pg.63]    [Pg.64]    [Pg.26]    [Pg.138]    [Pg.676]    [Pg.242]   
See also in sourсe #XX -- [ Pg.276 ]

See also in sourсe #XX -- [ Pg.116 ]



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ABCG

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