A X-ray structure

Figure 2-8. (A) X-ray structure of GPx dimer, (B) monomer used as die real system in ONIOM calculations, and (C) structure of the active site including two water molecules (Adapted from Prabhakar et al. [27]. Reprinted with permission. Copyright 2004 American Chemical Society.)...

Fig. 31.12 (a) X-ray structure of the enamide complex that corresponds to the correct" hand of product (from [58]). Solvent hydrogens and counterion are omitted for clarity, (b) Structure of the cation in (a), (c) Application of the Quadrant Rule by these authors. 

Figure 22 (a) X-Ray structure and (b) cyclic voltammogram in CH2CI2 solution... 

Figure 125 (a) X-Ray structure of [Cu(Hmal)]. Average bond lengths Cu-Nl... 

Figure56 (a) X-Ray structure of[Cu11( OETPP) J. (b) Side view along the N-Cu-Naxis. Average bond lengths Cu-N= 1.97 A Ca-N —1.38 A Ca-Cmeso = 1.40 A...

The termination module of surfactin synthetase is a 144 kDa four-domain enzyme responsible for the incorporation of the final amino acid (L-Leu) into the surfactin peptide and subsequent cyclization of the resulting product. The structure of the TE domain of this construct was previously solved. In the recently determined 2.6 A X-ray structure of the C-A-PCP-TE construct, the entire protein chain is evident in the electron density maps. " " The structural folds of the individual domains in this module are similar to structures of monomeric domains (Figure 13). The deviations observed in this multidomain structure include a slight difference in the hinge region of C domain subdomains and an orientation of the subdomains of the A domain that is not consistent with the open or closed conformations previously described. The A domain contains... 

Fig. 7.3. a) X-ray structure of the Cul complex 21 of ligand 14 b) Possible bimetallic intermediate involved 19 in si-face-selective ethyl transfer to 2-cyclohexenone. 

Fig. 14.8 Experimental ligand interactions with cytochrome P450 2C family. (A) X-ray structure ofthe sulfaphenazole derivate DMZ in rabbit CYP2C5 at 2.3 A resolution (PDB 1 N5B) from Wester et al. [191]. Only one ofthe two-ligand orientations for DMZ in accord with electron density is shown placing the benzylic methyl group in a 4.4 A distance to the heme iron. (B) X-ray structure of S-warfarin in human CYP2C9 at 2.55 A resolution (PDB 10G5) from Williams et al. [192]. The substrate is situated in a predominantly hydrophobic pocket. This binding mode places the 6- and 7-hydroxylation sites 10 A from the iron (arrow).

FIGURE 15. (a) X-ray structure of the jr-complexed lithium in the monomeric benzene complex of 2,6-bis(2,4,6-tri-isopropylphenyl)phenylhthium . (b) X-ray structure of the jr-complexed lithium in the dimeric 2,6-bis(2,6-di-isopropylphenyl)phenyUithium . It is evident from the Figure that the local environments around the lithium cations are similar... 

Figure 14.15 (a) X-ray structure of a model dimer repeat unit of peptide nanotubes made up from the self-... 

FIGURE 7.37. Chemical structure of biotin (a), X-ray structures of biotin (b) and biotin saturated streptavidin (c). 

Conversion of N02 to NO and/or N20 is carried out by the nitrite reductases NiRs). The 2.3 A X-ray structure of the NiR from A. cyclocastes has been determined (Fig. 5-13, Godden et al., 1992). Hulse et al. (1989) have suggested that reduction occurs by the general scheme,... 

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