A simple test to determine toxicity using bacteria

2 A SIMPLE TEST TO DETERMINE TOXICITY USING BACTERIA [Pg.1095]

Department of Biology, New Mexico State University, Las Cruces, NM, USA [Pg.1095]

The author has developed a simple, inexpensive and rapid method to measure toxieity using a baeterial indieator. This paper deseribes this test in detail. It also reviews the field of alternative tests for toxieity, tests not involving viable animals. [Pg.1095]

Often it is not known why the ehemieal is toxie. It is simply observed that animals eoming in eontaet with the toxin die at abnormally high rates. Obviously the first step in a study of a toxie ehemieal, is simply to determine if it is toxie. [Pg.1095]

Most animal tests are run with rats and miee, the usual laboratory animals. Rats and miee are rodents and they have a eaeeum, a ehamber that opens off the small intestine. The eaeeum eontains many mieroorganisms. It is not known what the role of the aeeum eould be in handling toxie ehemieals. This may influenee results with rats and miee. [Pg.1095]

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