A Rationale for New Methods in Drug Discovery

Turner, Sterrer, Wiesmiiller unit Meyer-Aimes 

Millions of individual chemical compounds Thousands of novel therapeutic targets 

105-106 compounds be screened with a single assay system. Using 96-well microtiter plate automated screening technology, a month would be required to screen a diversity of 10s at a rate of 50 plates per day. This rate must be cut by roughly a factor of ten for a research laboratory to remain competitive in today s pharmaceutical research environment. 

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