A-Hydroxyphosphonic acid

Of course, the use of tris(trimethylsilyl) phosphite213 214 provides facile access to the free a-hydroxyphosphonic acids. These silyl reagents have been used for the preparation of a wide range of a-substituted phosphonates and -phosphonic acids, starting with ketene,215 a-ketophosphonates,216 ketoesters,217 218 and a,P-unsaturated carbonyl compounds,207/219-221 as well as simple aldehydes and ketones.205 210/219 224 Their use for the preparation of compounds of significant biological interest has been reviewed.125... [Pg.56]

Acylphosphonic acids and esters Monoacyl phosphites a-Hydroxyphosphonic acid esters... [Pg.270]

X0 compds. and phosphinyl-formic acid esters 29, 614 a-Hydroxyphosphonic acid derivs. [Pg.261]

Abramov WS. On the interaction of dialkyl phosphonic acids with aldehydes and ketones. A new method for the synthesis of esters of a-hydroxyphosphonic acids. Dokl. Akad. Nauk S.S.S.R. 1950 73 487 89. [Pg.1467]

Cravotto G, Giovenzana GB, Pagliarin R, Palmisano G, Sisti M (1998) A straightforward entry into enantiomerically enriched / -Amino-a-hydroxyphosphonic acid derivatives. Tetrahedron Asym 9 745-748... [Pg.255]

Yokomatsu T, Yamagishi T, Shibuya S (1993) Stereodivergent synthesis of J -amino-a-hydroxyphosphonic acid derivatives by Lewis acid mediated stereoselective hydrophosphonylation of a-amino aldehydes. Tetrahedron Asym 4 1401-1404... [Pg.263]

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