A Detailed Look at the Hydrogen Bond Donor Features of HFIP

A Detailed Look at the Hydrogen Bond Donor Features of HFIP 

For understanding the catalytic properties of fluorinated alcohols, it is necessary to take a closer look at the hydrogen bond donor properties of HFIP and the factors by which they are influenced [16]. The hydrogen bond donor ability of fluorinated 

Furthermore, the hydrogen bond donor ability of an HFIP hydroxyl group is greatly enhanced upon coordination of a second or even third molecule of HFIP 

Therefore, our mechanistic investigation of the epoxidation of alkenes with hydrogen peroxide, as summarized in Section 4.3.1.1, will be constrained to reaction pathways which (i) involve H FIP in an sc or even sp conformation and (ii) to hydrogen-bonded HFIP aggregates comprising up to four alcohol monomers. 

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