D-a-Glucose

Example Hrady investigated classical dyriam ics of a-d-glucose in... 

Example Brady investigated classical dynamics of a-d-glucose in water.In this simulation, 207 water molecules surrounded one a-d-glucose. The system was in a cubic box with periodic boundary conditions. During the simulation, several hydroxyl group transitions occurred. These transitions are normally unlikely with an in vacuo simulation. 

You can detect hydroxyl group transitions by plotting dihedral angles versus time over the course of the simulation. This is the distance history. Brady investigated the distance history of water 19. Brady, J.W. Molecular dynamics simulations of a-d-glucose in aqueous solution. 

Aminoglycoside Biosynthesis. The biosynthesis of the aminoglycosides has been extensively studied and reviewed (117—119). Perhaps the most interesting aspect is the biosynthesis of 2-deoxystreptamiae (1, R = H), in which the C-1 and C-6 of a D-glucose molecule become the C-1 and C-2 of 2-deoxystreptamiae by way of the intermediate 2-deoxy-j //(9-iaosose. The details of this conversion are stiU unclear. 

Commercial dextrose products are produced in both dry and symp forms. Dry products are prepared by crysta11i2ation (qv) to either an anhydrous, DHnO, or hydrated, H20, form. These include dextrose hydrate [16824-90-17, anhydrous a-D-glucose [26655-34-5] (1), and anhydrous... 

As a final example we consider noncovalent molecular complex formation with the macrocyclic ligand a-cyclodextrin, a natural product consisting of six a-D-glucose units linked 1-4 to form a torus whose cavity is capable of including molecules the size of an aromatic ring. Table 4-3 gives some rate constants for this reaction, where L represents the cyclodextrin and S is the substrate ... 

FIGURE 7.23 The starch phosphorylase reaction cleaves glucose residues from amy-lose, producing a-D-glucose-l-phosphate. 

Glucose oxidase is specific for P-D-glucose and where a-D-glucose is the available substrate, prior conversion from the a to the P form is required. 

J. Boerio-Goates, "Heat-Capacity Measurements and Thermodynamic Functions of Crystalline a-D-Glucose at Temperatures from 0 K to 350 K.". J. Chem. Thermodyn.. 23, 403-409 (1991). 

Amino-2-deoxy-a-D-glucose (a-D-Glucosamine) from Crustacean Shell, M. Stacey and J. M. Webber, Methods Carbohydr. Chem., 1 (1962) 228-230. 

The conformational symbols for enantiomers are different. It is therefore important to state in the context whether the d or the L form is under consideration. Enantiomers have the same reference plane (see 2-Caib-7.3), and it should be noted that the mirror image of a-D-glucose-4Ci is a-L-glucose-C4. 

Chiral nitrogen chelates derived from sugars were prepared by Ruffo [48], introducing diimines and diamines functionalities on inexpensive monoses, a-D-glucose and a-D-mannose. 

Figure 13-1. o-Glucose. A straight chain form. B a-D-glucose Haworth projection. C a-o-glucose chair form. 

Glycogen is the major storage carbohydrate in animals, corresponding to starch in plants it is a branched polymer of a-D-glucose. It occurs mainly in liver (up to 6%) and muscle, where it rarely exceeds 1%. However, because of its greater mass, muscle contains about three to four times as much glycogen as does liver (Table 18—1). 

---