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A8-Tetrahydrocannabinol

This compound and its related acidic form, A8-tetrahydrocannabinolic acid (A8-THCA, 2.13) are structural isomers of A9-THC. Although it is the thermodynamically stable form of THC, A8-THC (2.14) contributes approximately only 1% to the total content of THC in C. sativa. In the synthetic production process, A8-THC is formed in significantly higher quantities than in plants. [Pg.6]

There are approximately 400 chemicals in the cannabis plant, 61 of which are unique and may be called cannabinoids. The most common psychoactive cannabinoid is A9-tetrahydrocannabinol (A9-THC) (Robbers et al. 1996) (figure 10.4). Other psychoactive cannabinoids include A8-tetrahydrocannabinol (A8-THC), ll-hydroxy-A8-tetrahydrocannabinol (11-OH-A9-THC), and 9-nor-9 j8-hydroxyhexahydrocannabinol p-... [Pg.410]

A8 -tetrahydrocannabinol were quantitatively separated with respective retention volumes of 6.37 and 6.62 ml (the dead volume between the UV detector and the collection point was 0.46 ml as determined by the iodoform test). Cannabidiol in the same system had a retention volume of 6.06 ml. [Pg.20]

A9 Tetrahydrocannabinol and ll-hydroxy-A -tetra-hydrocannabinol were quantitatively separable on the reverse phase HPLC system at 47% (or less) acetonitrile in water. The collection efficiencies in the chosen ranges were 98% of the recoverable radioactivities of 8H-ll-hydroxy-A8-tetrahydrocannabinol and l c-A8-tetrahydrocannabinol (Fig. 5). A8- and A8-Tetrahydro-... [Pg.20]

Figure 4.3 Electron-impact mass spectrum of the TMS ether of A8-tetrahydrocannabinol. Figure 4.3 Electron-impact mass spectrum of the TMS ether of A8-tetrahydrocannabinol.
Papahatjis DP, Nikas SP, Andreou T, Makriyannis A (2002) Novel l ,r-chain substituted A8-tetrahydrocannabinols. Bioorg Med Chem Lett 12 3583-3586... [Pg.47]

Pertwee RG, Fernando SR, Griffin G, Ryan W, Razdan RK, Compton DR, Martin BR (1996b) Agonist-antagonist characterization of 6 -cyanohex-2 -yne-A8-tetrahydrocannabinol in two isolated tissue preparations. Eur J Pharmacol 315 195-201... [Pg.48]

Ross RA, Gibson TM, Stevenson LA, Saha B, Crocker P, Razdan RK, Pertwee RG (1999b) Structural determinants of the partial agonist-inverse agonist properties of 6 -azidohex-2 -yne-A8-tetrahydrocannabinol at cannabinoid receptors. Br J Pharmacol 128 735-743... [Pg.49]

Huffman JW, MUler JRA, Liddle J, Yu S, Thomas BF, WUey JL, Martin BR (2003b) Structure-activity relationships for l, l -dimethylalkyl-A8-tetrahydrocannabinols. Bioorg Med Chem 11 1397-1410... [Pg.240]

Tetradecanal-14-ol, 252 Tetraethylammonium acetate, 277 Tetraethylammonium bromide, 140 Tetraethyl dimethylaminomethylene-diphosphonate, 277—278 Tetraethyl orthocarbonate, 285 A8-Tetrahydrocannabinol, 307 A9-Tetrahydrocannabinol, 307 1,2,3,4-Tetrahydrocarbazole, 231... [Pg.202]

See other pages where A8-Tetrahydrocannabinol is mentioned: [Pg.6]    [Pg.159]    [Pg.84]    [Pg.368]    [Pg.26]   
See also in sourсe #XX -- [ Pg.22 , Pg.30 , Pg.195 , Pg.515 , Pg.537 ]

See also in sourсe #XX -- [ Pg.195 ]



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