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99mTc-sestamibi

Figure 7.12 (A) 99mTc-sestamibi (Cardiolite ) and (B) "mTc-tetrofosmin (Myoview ). Figure 7.12 (A) 99mTc-sestamibi (Cardiolite ) and (B) "mTc-tetrofosmin (Myoview ).
Dilsizian V, Arrighi JA, Diodati JG, Quyyumi AA, Alavi K, Bacharach SL et al. Myocardial viability in patients with chronic coronary artery disease. Comparison of 99mTc-sestamibi with thallium reinjection and [18F]-fluorodeoxyglucose. Circulation 1994 89 578-587... [Pg.36]

Fig. 14 Time variation of a heart/lung and b heart/liver ratios for the complexes 99mTcN-DBODC (squares), 99mTc-Sestamibi (circles) and 99mTc-Tetrofosmin (triangles) measured at a specific time after injection in rats. The values are expressed as the ratio between the activity localized in the heart and the activity localized in the lungs and the liver, respectively... Fig. 14 Time variation of a heart/lung and b heart/liver ratios for the complexes 99mTcN-DBODC (squares), 99mTc-Sestamibi (circles) and 99mTc-Tetrofosmin (triangles) measured at a specific time after injection in rats. The values are expressed as the ratio between the activity localized in the heart and the activity localized in the lungs and the liver, respectively...
Hexakis(2-methoxyisobutylisonitrile)technetium-99m (commonly known as [99mTc]Sestamibi) (20a), although originally developed as a radiopharmaceutical for myocardial perfusion imaging [59,60], was the first metal complex... [Pg.165]

Several clinical studies have shown the feasibility of interrogating Pgp transport activity in vivo with imaging cameras commonly available in nuclear medicine facilities [71-73,124-129]. In general, 99mTc-Sestamibi pharmacokinetic data are extracted from tumor images over time and correlated with immuno-... [Pg.172]

Furthermore, in addition to the in vitro and animal laboratory studies cited earlier, clinical blockade of Pgp-mediated extrusion of 99mTc-Sestamibi from tissues and tumors of patients has been imaged following treatment with highly selective and potent Pgp modulators such as PSC 833 (valspodar), VX-710 (biricodar), and XR-9576 (tariquidar) [6, 51, 71, 72, 74]. A two-step protocol for imaging MDR reversal in patients is under evaluation and this may provide a noninvasive method to determine the effectiveness of MDR... [Pg.173]

Agrawal, M., Abraham, f., Balis, F.M., Edgerly, M., Stein, W.D., Bates, S., Fojo, T, and Chen, C.C. (2003) Increased 99mTc-sestamibi accumulation in normal liver and drug-resistant tumors after the administration of the glycoprotein inhibitor, XR9576. Clinical Cancer Research, 9 (2), 650-656. [Pg.46]

Miller TD, Christian TF, Hopfenspirger MR, et al. Infarct size after acute myocardial infarction measured by quantitative tomographic 99mTc sestamibi imaging predicts subsequent mortality. Circulation 1995 92(3) 334-41. [Pg.78]

Bacher-Stier C, Sharir T, Kavanagh PB, et al. Postexercise lung uptake of 99mTc-sestamibi determined by a new automatic technique validation and application in detection of severe and extensive coronary artery disease and reduced left ventricular function. J Nucl Med 2000 41(7) 1190-7. [Pg.79]

Maffioh L, Steens J, Pauwels E and Bombardieri E. Applications of 99mTc-sestamibi in oncology. Tumori 1996 82 12-21. [Pg.638]

Doukaki S, Arico M, Bongiorno MR. Erythroderma related to the administration of 99mTc-sestamibi the first report. J NucI Cardiol 2010 17 520-2. [Pg.760]

See other pages where 99mTc-sestamibi is mentioned: [Pg.963]    [Pg.228]    [Pg.101]    [Pg.102]    [Pg.165]    [Pg.166]    [Pg.173]    [Pg.173]    [Pg.173]    [Pg.494]    [Pg.64]    [Pg.64]    [Pg.241]    [Pg.144]    [Pg.72]   
See also in sourсe #XX -- [ Pg.9 ]



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