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7V-hydroxysuccinimide

Figure 1 Conjugation reactions for coupling peptides to the surface of preformed liposomes. Functionalized lipophilic anchors were incorporated into liposomes and reacted with the peptides in aqueous media. Reactive endgroup functions (A) maleimide (B) bromo- or iodoacetyl (C) 2-pyridyldithio (D) carboxylic acid (E) />-nitrophenyl carbonate and (F) hydrazide. Abbreviations EDC, l-ethyl-3-(3-dimethylaminopropyl)carbodiimide NHS, 7V-hydroxysuccinimide. Figure 1 Conjugation reactions for coupling peptides to the surface of preformed liposomes. Functionalized lipophilic anchors were incorporated into liposomes and reacted with the peptides in aqueous media. Reactive endgroup functions (A) maleimide (B) bromo- or iodoacetyl (C) 2-pyridyldithio (D) carboxylic acid (E) />-nitrophenyl carbonate and (F) hydrazide. Abbreviations EDC, l-ethyl-3-(3-dimethylaminopropyl)carbodiimide NHS, 7V-hydroxysuccinimide.
D-(+)-Biotin 7V-hydroxysuccinimide ester (+-biotin 7V-succinimidyl ester) [350]3-72-0 M 342.4, m 210 , 212-214°, [a]p +53 (c 1, Me2NCHO). Recrystd from refluxing isoPrOH and dried in a vacuum over P2O5 + KOH. (Jasiewicz et al. Experimental Cell Biology 100 213 7976]. [Pg.467]

Acetylation of 7V-terminal amines by means of 7V-hydroxysuccinimide (or its analogue) [29] or succinic anhydride (or its analogue), or esterification of C-terminal carboxylic acids and of Asp and Gin [98],... [Pg.509]

Positions 81-104 of ribonuclease Ti 24 benzyloxycarbonyl, f-butoxycarbonyl hydrazide diazotization, nitrophenyl esters, 7V-hydroxysuccinimide a... [Pg.480]

Scheme 4-17. Template synthesis of [Fe(L1019)] (a) C6H5CH2CI, KI, K2CO3, acetone reflux, 72 h, 85% (b) NaOH, DMF/H2O, reflux, 9 h, 94% (c) 7V-hydroxysuccinimide, dicyclohexyl-carbodiimide, dioxan, 72% (d) H2/5% Pd-C, ethyl acetate, room temperature, 1 h, 100% (e) FeCla, (C2Hs)3N, DMF or DMSO, not isolated (f) tris(2-aminoethyl)amine (2 equivalents), room temperature, 14 h (g) 4-(dimethylaniino)-pyridine, 65°C, 5 days, 70%. Scheme 4-17. Template synthesis of [Fe(L1019)] (a) C6H5CH2CI, KI, K2CO3, acetone reflux, 72 h, 85% (b) NaOH, DMF/H2O, reflux, 9 h, 94% (c) 7V-hydroxysuccinimide, dicyclohexyl-carbodiimide, dioxan, 72% (d) H2/5% Pd-C, ethyl acetate, room temperature, 1 h, 100% (e) FeCla, (C2Hs)3N, DMF or DMSO, not isolated (f) tris(2-aminoethyl)amine (2 equivalents), room temperature, 14 h (g) 4-(dimethylaniino)-pyridine, 65°C, 5 days, 70%.
See other pages where 7V-hydroxysuccinimide is mentioned: [Pg.109]    [Pg.413]    [Pg.864]    [Pg.864]    [Pg.109]    [Pg.413]    [Pg.864]    [Pg.864]    [Pg.304]   
See also in sourсe #XX -- [ Pg.290 , Pg.359 ]



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