Zincation Mediated by Amidozinc Complexes

Investigations by Mulvey and his group have uncovered very unusual structures associated with the mixed alkali metal-zinc reagents.For example, it has been found that a 1 1 mixture of KN(SiMe3)2 and ZnfNfSiMe, ), readily deprotonates toluene [Equation (7.1)] to afford 

The alkali-metal mediated activation of toluene prompted further work involving more 

Kondo and coworkers that the use of the reagent LiZnBuX (NCMe2(CH2)3CMe2), which 

More recent work involving anisole as the aromatic substrate has shown that this I-------------------------------------------------1 

Treatment of ZnMe2 with LiNCMe2(CH2)3CMe2in the presence of tmeda afforded the conventional zincate product in accordance with Equation (7.5). 

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