X-linked Lymphoproliferative disease

Ma CS, Pittaluga S, Avery DT et al 2006 Selective generation of functional somatically mutated IgMCD27, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative disease. Clin Invest 116 322—333... [Pg.72]

Nichols KE, Ma CS, Cannons L, Schwartzberg PL, Tangye SG 2005b Molecular and cellular pathogenesis of X-linked lymphoproliferative disease. Immunol Rev 203 180—199... [Pg.72]

Parolini S, Bottino C, Falco M et al 2000 X-linked lymphoproliferative disease. 2B4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cells. Exp Med 192 337—346... [Pg.72]

X-linked recessive lymphoproliferative disease (XLP), first characterized clinically in 1975, is associated with susceptibility to B cell-tropic Epstein-Barr virus (EBV) (Purtilo et al 1975). The clinical manifestations are heterogeneous but reflect impaired host control of EBV-infected B cells, and include fulminant infectious mononucleosis with haemophagocytosis (excessive T cell-mediated macrophage activation in response to the primary infection of B cells with EBV), B cell... [Pg.68]

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