Wurtz-Fittig reaction

Wurtz - Fittig reaction. The interaction of an aryl halide, alkyl hahde and sodium gives a reasonable yield of an alkyl aryl hydrocarbon, for example ... 

Two mechanisms have been proposed for the Wurtz reaction (compare Section III,7) and for the Wurtz-Fittig reaction. According to one, sodium reacts with the alkyl halide to produce a sodium halide and a free radical, which subsequently undergoes coupling, disproportionation, etc. ... 

Williamson synthesis Wohl-Ziegler reaction Wolff rearrangement Wolff Kishner reduction Wurtz reaction Wurtz-Fittig reaction... 

Wurster process Wurster salts Wurtz-Fittigcoupling Wurtz-Fittig reaction Wurtzite... 

Poly-p-phenylene has been prepared in the laboratory by a variety of methods, including the condensation of p-dichlorobenzene using the Wurtz-Fittig reaction. Although the polymer has a good heat resistance, with decomposition... 

The coupling of alkyl halides 1 upon treatment with a metal, e.g. elemental sodium, to yield symmetrical alkanes 2, is called the Wurtz reaction. Aryl alkanes can be prepared by the Wurtz-Fittig reaction, i.e. the coupling of aryl halides with alkyl halides. 

The synthetic applicability is rather limited, due to the various side-reactions observed, such as eliminations and rearrangement reactions. The attempted coupling of two different alkyl halides in order to obtain an unsymmetrical hydrocarbon, usually gives the desired product in only low yield. However the coupling reaction of an aryl halide with an alkyl halide upon treatment with a metal (the Wurtz-Fittig reaction) often proceeds with high yield. The coupling of two aryl halides usually does not occur under those conditions (see however below ) since the aryl halides are less reactive. 

By analogy to the utilization of Zn° in the Wurtz-Fittig reaction (31), Scheme [6] illustrated for Zn° is proposed to account for the observed reaction between DBDPO and any other active metals such as Sb° or Bi°. 

Wurtz-Fittig reaction org chem A modified Wurtz reaction in which an aromatic... 

A mixture of an alkyl halide and aiyl halide gives an alkylarene when treated with sodium in dry ether and is called Wurtz-Fittig reaction. 

In the Wurtz Reaction, both halides are alkyl. For the Wurtz-Fittig Reaction, there is one alkyl and one aryl group, while in the Fittig Reaction, both coupling partners are aryl halides. 

An alternative to produce H-H arranged PIB is the coupling via the Wurtz-Fittig reaction. This is the coupling of alkyl halides by the treatment with metallic sodium or other metals such as lithium and zinc. However, this type of reaction results in substantially branched polymers with a comparatively low molecular weight (19). 

Preparation1 This reagent can be prepared in 66% yield by reaction of triflic acid with isopropenyltrimethylsilane, CH2=C(CH3)Si(CH3)3, which is available from Petrarch or which can be prepared by a Wurtz-Fittig reaction of 2-chloro-propene with sodium and chlorotrimethylsilane in ether/HMPT. 

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