Wound Second intention

Use on surgical wounds has been cautioned as wounds being healed by second intention (left open to heal from the base outward) treated with aloe vera leaf gel have been observed to have increased healing time in one study (Schmidt and Greenspoon 1991), although other studies have indicated beneficial effects of aloe vera leaf gel or extract on wound healing or psoriasis (Fulton 1990 Syed et al. 1996). 

The second example was the 6.5mm Jap rifle round, where, probably intentionally from the wounding point of view, the Pb core was thickened considerably at the base compared to the upper portion. This bullet, in spite of its small caliber and lowish velocity, tumbled badly upon hitting tissue, and caused serious wounds... 

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