Wisconsin Regional Primate Research Center

In 1987, the National Institute of Ageing in Baltimore, Maryland and the Wisconsin Regional Primate Research Center in Madison, began two trials in primates — 200 rhesus and squirrel monkeys. In April 2001, the Wisconsin team, headed by Richard Weindruch, published an interim report on the effects of calorie restriction on gene expression, and thus the types and levels of proteins synthesized, in rhesus monkeys. To measure the effects, they determined which out of a selected sample of 7000 genes were switched on and which were switched off in the calorie-... 

Davenport (cf., footnote 2) has made available an unpublished sunmary (dated Aug. 14, 1963) of a substantial number of behavioral studies on TCAP, all conducted at the Wisconsin Regional Primate Research Center. Most of these used rats, but some used squirrel, stump-tall, or rhesus monkeys. Considerable variation in the effect of TCAP was seen, and in some studies even decremental effects on acquisition and retention were indicated. Nevertheless, facllltatlve effects were often seen, especially when dosage was chronic. 

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