Windaus, Adolf Otto

WIndaus, Adolf Otto Reinhold (1876-1959) German biochemist who studied the drug digitalis, established the structure of cholesterol, and researched vitamin D and some of the B vitamins. He was awarded the 1928 Nobel Prize in chemistry. 

Adolf Otto Windaus Germany sterols relationship with vitamins... 

Adolf Otto Reinhold Windaus Constitution of the sterols and their connection with the vitamins... 

Adolf Otto Reinhold Windaus (Germany) for his research into the constitution of the sterols and their connection with the vitamins. Windaus was awarded the Nobel Prize for discovering that cholesterol (a sterol) was removed to cholecalcif-erol (vitamin D3) through a series of several steps. One of Windaus doctoral students, Adolf Buteneindt, was himself a Nobel laureate. 

Two German chemists, Heinrich Otto Wieland (1877-1957) and Adolf Windaus (1876-1959), each received a Nobel Prize in chemistry (Wieland in 1927 and Windaus in 1928) for work that led to the determination of the structure of cholesterol. 

Two German chemists, Heinrich Otto Wieland (1877-1957) and Adolf Windaus (1876- ), worked out the structure of steroids and related compounds. (Among the steroids are a number of important hormones.) Another German chemist, Otto Wallach (1847-1931), painstakingly elucidated the structure of terpenes, important plant oils (of which menthol is a well-known example), while still another, Hans Fischer (1881-1945), established the structure of heme, the coloring matter of blood. 

The beginnings of steroid chemistry go back to Adolf Windaus (1876-1959), who laid the foundations of this captivating field in 1905. Important contributions came from Adolf Butenandt (1903-1995) and Heinrich Otto Wieland (1877-1957). [15] Oestrone was the first sex hormone to he isolated from the urine ofpregnant women in 1929 hy Butenandt in Gottingen. [16] Later,heused... 

This material was also detectable in crude cholesterol from animals. Later it was found, that irradiation of ergosterol, a steroid from baker s yeast, led to a mixture of products with extraordinarily high anti-rachitic activity. At the end of the 1920s, Otto Rosenheim, Thomas Arthur Webster and Adolf Windaus succeeded, independently of each other, in isolating first the unpurified Vitamin D (Vitamin Dj, a mixture of ergocalciferol and lumisterolj) and later the pure crystalline Vitamin D (Vitamin D2, ergocalciferol). The structure determination followed by classical chemical degradation. 

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