Widows

At the age of thirty-three. Watt wrote, Of all things in life, there is nothing more foolish than inventing. Just widowed with six children, he had put away his love of science, engineering and fine technical instrumentation to feed his family by contracting to suixiey for the Caledonian canal. Bankruptcy of his financial partner in steam development, John Roebuck, had derailed his efforts to improve the steam engine. 

Mr. Harris, age 72 years, is a widower who has lived alone since his wife died 5 years ago. He has been prescribed warfarin to take at home after his dismissal from the hospital. Determine which questions concerning the home environment would be important to ask Mr. Harris to prepare him to care for himself and prevent any complications associated with the warfarin. 

Antivenins are used for passive, transient protection from the toxic effects of bites by spiders (black widow and similar spiders) and snakes (rattlesnakes, copperhead and cottonmouth, and coral). The most effective response is obtained when the drug is administered within 4 hours after exposure... 

That s good, him being so lately married and she with child. I would not like to think of her a widow. ... 

I heard one complain, and could tell even from that distance that it was Margaret Beaufort. Edmund Tudor got her boy Henry on her when she was but twelve years old, and she was a widow before she was delivered. No wonder, then, that she had neither chick nor child more, as Mai would have said, though married again long since. I could not reproach her, so my patience broke with the lot of them. Go back, then I do not want you here if you can do nothing but whimper. They hesitated. Go on Go If I have Mai, I have no need of you. ... 

And not all the new gold that the alchemists promised us seemed likely to satisfy George of Clarence, or the old gold snatched from Warwick s widow, or the blood of my father and brother, or even Jason s fleece itself. Nothing but the gold of his brother s crown would do. At last even Edward s power of forgiveness was worn to shreds. 

I drink. Is it thus with all boys I, too, wanted to conquer the world, though more of it was offered me than a widow of Sheriff... 

Elysabeth s boy, Richard Grey, is dead. I sent him a scarlet whip-top from Sandwich, the day we were captured by Warwick s men. Once I met him, stale-drunk, outside a whorehouse in Southwark. You will not tell my mother he said. He was no more than Stephen s age. Stephen has a widowed mother with no love or care in her life but him Richard s mother was a queen. She loved him very much, but she had too much, too many, to care for besides. 

To Elizabeth, perhaps, newly widowed, brought full circle back to her old condition, alone. 

I hear the sharp shuffle and murmur of the lay-sisters rising to go about their tasks in the garden, the kitchen, the orchard. The silence of the holy sisters calls me to join them. The latch rises my woman is coming to help me dress, though it is an hour or more till Prime. Even with plain old gowns and no more headdress than a widow s hood it takes time, for we are both old, and my bones ache, and there is little flesh on them. I move slowly. 

Neurotoxin that produces a massive release of transmitters from cholinergic and adrenergic nerve endings resulting in continuous stimulation of muscles. It also induces formation of an ion channel allowing the inward flow of calcium ions into the nerve cell. It is a white powder obtained from the venom of the black widow spider. 

Whereas, the members of the Senate, by this resolution, would like to extend their heartfelt condolences to his widow, Mrs. Sherry Randle Shealey and their three sons, Chad, Travis, and Brent, and to other members of his family upon the death of this truly wonderful man. Now, therefore,... 

Casern, M. L., Tran, L. P. P., and Moore, A. M. F. (2002). Ultrastructure of the major ampullate gland of the black widow spider, Latrodectus hesperus. Tissue Cell 34, 427-436. 

Widow Bascomb knew perfectly well there was not, but she reached for a small pile of letters in a pigeonhole on her right and glanced over them rapidly. Her sour visage and rasping voice softened perceptibly as she smiled on the little old man before her. 

He placed the bread and the pie back upon the table and stood looking at them long and earnestly. He knew of one who needed them far more than he did, a poor widow over in the hollow, whose five small children, sickly, starved little creatures, were more than half the time crying with cold and hunger. He opened the package of tobacco, filled his pipe and sat down in his chair by the stove to smoke and think. 

Widow spider venom Black widow Nervous system... 

The amount of acetylcholine present in the synapse and the amount of time that it remains there are critical. For example, the venom of the black widow spider is highly neurotoxic. It contains a protein known as a-latrotoxin that elicits the release of massive amounts of acetylcholine at the neuromuscular junction. Too much of a good thing can be a serious problem. 

We noted above that too much acetylcholine in the synapse or at a neuromuscular junction can be a problem black widow spider venom works that way by causing massive release of this neurotransmitter. There is another way to accomplish the same thing inhibit the normal route by which acetylcholine once released is subsequently removed. That route is degradation by acetylcholinesterase, an enzyme that catalyzes... 

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