West Pharmaceutical Services

West Pharmaceutical Services Plant in Kinston, North Carolina, 29 January 2003, and CTA Acoustics Manufacturing Plant in Corbin, Kentucky, 20 Februaiy 2003. Reference U.S. Chemical Safety Board (CSB) www.csb.gov/index.cjmPfolder = completed investigations bpage = info INV LD=34 and ID = 35... 

WEST PHARMACEUTICAL SERVICES INC WESTLAKE CHEMICAL CORPORATION WINPAK LTD WR GRACE CO ZEON CORPORATION... 

West Analytical Services WEST PHARMACEUTICAL SERVICES INC... 

In another incident, on January 29, 2003, an explosion and fire destroyed the West Pharmaceutical Services plant in Kinston, North Carolina, causing six deaths, dozens of injuries, and hundreds of job losses. The facility produced rubber stoppers and other products for medical use. The investigators fovind that the fuel for the explosion was a fine plastic powder used in producing rubber goods. Combustible polyethylene dust accumulated above a suspended ceiling over a manufacturing area at the plant and was ignited by an unknown event (Fig. 2.1). 

Figure 2.1 Dust explosion kills six, destroys West Pharmaceutical Services Plant, Kinston, NC (January 29, 2003). Source www. chemsafety.gov/index.cfm )...

Fig. 2 Typical rubber syringe plungers (A) Plunger for 10-mL sterile-empty syringe (B) Plunger for sterile-prefilled dental cartridge (C) Plunger for ImL sterile-empty syringe (D) Tip cap for Luer Tip syringe. (Photograph provided by West Pharmaceutical Services, Inc.)...

West Pharmaceutical Services WP 101 Gordon Drive, Lionville, PA 19341, USA 1-800-231-3000 www.westpharma.com... 

Frances L. DeGrazio West Pharmaceutical Services, Inc., Lionville, Pennsylvania, U.S.A. 

The West LyoTec System Manual, Technology to Optimize Your Cost Effective Lyophilization Process. West Pharmaceutical Services Inc. (formerly... 

What is true for the container in the container-closure system is equally true for the closure alone and, essentially, for the elastomeric stoppers, generally butyl rubber, which cap the vial. Fran DeGrazio from West Pharmaceutical Services has done a lot of research in this field and studied many alternatives to their formulation trying to keep down the extractables (essentially volatile) and leachables and prevent adsorption of oils, waxes, polymers, and others on the freeze-dried plug. 

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