Vulvovaginal candidiasis recurrent

Recurrent vulvovaginal candidiasis, defined as four or more infections per year, requires long-term suppressive therapy for 6 months. 

Vulvovaginal candidiasis (VVC) refers to infections in individuals with or without symptoms who have positive vaginal cultures for Candida. Depending on episodic frequency, VVC can be classified as either sporadic or recurrent. This classification is essential to understanding the pathophysiology, as well as the pharmacother-... 

Recurrent vulvovaginal candidiasis (RV VC) is defined as having more than four episodes of VVC within a 12-month period. Fewer than 5% of women develop RVVC, and its pathogenesis is poorly nn-derstood. A proper diagnosis should be obtained to mle ont other infections or nonmycotic contact dermatitis. Most of the therapies are empirical and not based on proper randomized, controlled trials. Treatments include induction therapy, which should be administered for a minimum of 14 days or until clinical remission and negative cultures have been obtained. Table 118-2 fists the medications used for induction therapy. Induction therapy should be followed by a... 

Clotrimazole has been reported to cure dermatophyte infections in 60 to 100% of cases. The cure rates in cutaneous candidiasis are 80 to 100%. In vulvovaginal candidiasis, the cure rate is usually above 80% when the 7-day regimen is used. A 3-day regimen of 200 mg once a day appears to be similarly effective, as does single-dose treatment (500 mg). Recurrences are common after all regimens. The cure rate with oral troches for oral and pharyngeal candidiasis may be as high as 100% in the immunocompetent host. 

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