Vitellogenin expression

Phytoestrogens Isoflavones genistein ER/1, ERa" 3 Agonist Induces vitellogenin expression,... 

Korte J.J, M.D. Kahl, K.M. Jensen, M.S. Pasha, L.G. Parks, G.A. LeBlanc, and G.T. Ankley (2000). Fathead minnow vitellogenin Complementary DNA sequence and messenger RNA and protein expression after 17 3-estradiol treatment. Environmental Toxicology and Chemistry 19 972-981. 

Guidugli-Lazzarini, K.R., do Nascimento, A.M., Tanaka, E.D., Piulachs, M.D., Hartfelder, K., Bitondi, M.G. and Simoes, Z.L. (2008). Expression analysis of putative vitellogenin and lipophorin receptors in honey bee (Apis mellifera L.) queens and workers. J. Insect Physiol., 54, 1138-1147. 

NP is able to interact and bind to the estrogen receptor, and is therefore capable of modulating estrogen receptor-mediated gene expression, such as that responsible for vitellogenin in fish. However, the estrogenic potency of NP is 1000 times less than that of 17)S-estradiol. 

Several assays, such as the ultra-sensitive luminescent ELRA developed by Seifert (2004) with a detection limit of 20 ng L-1 for 17 (3-estradiol, have been reported in the literature. Although these assays are simple to use, many factors, such as differences in culture conditions, cell density or cell-line clones, affect the potency of estrogenic substances, and that makes the standardization of these methods difficult. The induction of several proteins or enzyme activities (e.g. the increasing levels of alkaline phosphatase, cathepsin D, prolactin and vitellogenin as a consequence of progestogens) has also been used to study estrogenicity. However, expression of these proteins or enzyme activities is restricted to specific cell lines and cannot be extrapolated to other tissues or species. 

Hemmer, M.J., B.L. Hemmer, C.J. Bowman, K.J. Kroll, L.C. Folmar, D. Marcovich, M.D. Hoglund and N.A. Denslow. Effects of p-nonylphenol, methoxychlor, and endosulfan on vitellogenin induction and expression in sheepshead minnow (Cyprinodon variegatus). Environ. Toxicol. Chem. 20 336-343, 2001. 

Flouriot, G., F. Pakdel, B. Ducouret and Y. Valotaire. Influence of xenobiotics on rainbow trout liver estrogen receptor and vitellogenin gene expression. J. Mol. Endocrinol. 15 143-151, 1995. 

Juvenile hormone-regulated locust vitellogenin genes Lack of expression after transfer into Drosophila." Arch. Insect Biochem. Physiol. Suppl. 1 35-46. 

Jost, J.P., Sahiz, H.P., McEwan, I. et ed. (1990). Tissue specific expression of avian vitellogenin gene is correlated with DNA hypomethylation and in vivo spedfic-DNA interactions. Philos. Trans. R. Soc. Land, 326B, 231—40. 

Shyu A-B, Raff RA, Blumenthal T (1986) Expression of the vitellogenin gene in female and male sea urchin. Proc Natl Acad Sci USA 83 3865-3869... 

POUSIS C, DE GIORGI C, MYLONAS C C, BRIDGES C R, ZUPA R, VASSALLO-AGIUS R, DE LA gXndara f, dileo c, DE METRIC G and CORRIERO A (2011) Comparative study of liver vitellogenin gene expression and oocyte yolk accumulation in wild and captive Atlantic bluefin tuna Thunnus thynnus T, ). Animal Reproduction Science, 123, 98-105. 

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