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Visual cortex critical period

Critical periods are those in which the synaptic circuitry of a given brain region becomes stabilized in a functionally optimized conformation. The cerebral cortex and other brain structures contain functional maps for the activities characteristic of a species. The best example is the ocular dominance columns and other physical and functional characteristics of the circuitry within the visual cortical system that process information derived from the left and right visual fields, producing a map of the visual world. Other internal maps exist for the body (somatosensory, motor corti-... [Pg.14]

Reid SNM, Romano C, Hughes T, Daw NW (1995) Immunohistochemical study of two phosphoinositide-linked metabotropic glutamate receptors (mGluRla and mGluR5) in the cat visual cortex before, during, and after the peak of the critical period for eye-specific connections. J Comp Neurol 355 410-411. [Pg.96]

Huang ZJ, Kirkwood A, Pizzorusso T, Porciatti V, Morales B, Bear ME, Maffei L, Tonegawa S (1999) BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex. Cell 98 739-755. [Pg.92]

Experience and activity-dependent maturation of peiisomatic GABAergic iimervation in primary visual cortex during a postnatal critical period. J Neurosci 24 9598-9611. [Pg.107]

Fagiolini M, Hensch TK (2000) Inhibitory threshold for critical-period activation in primary visual cortex. Nature 404 183-186. [Pg.107]

Iwai Y, Fagiolini M, Obata K, Hensch TK (2003) Rapid critical period induction by tonic inhibition in visual cortex. J Neurosci 23 6695-6702. [Pg.108]

Dudek, S.M. and Bear, M.F. (1989). A biochemical correlate of the critical period for synaptic modification in the visual cortex. Science 246 673-675. [Pg.525]


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