Virus crystallography

Protein, DNA and virus crystallography with a focused imaging proportional counter. Science 232, 1127-1132. 

Fourme, R., et al. (2002). Opening the high-pressure domain beyond 2 kbar to protein and virus crystallography-technical advance. Structure (Camb) 10,1409-1414. 

Tsuruta, H., et al. (1998). Imaging RNA and dynamic protein segments with low-resolution virus crystallography experimental design, data processing and imph-cations of electron density maps. /. Mol. Biol. 284, 1439-1452. 

Further reductions in exposure time and hence radiation damage in virus crystallography may accrue from the use of white beam (modified) Laue methods preliminary work on this is in progress (Bloomer and Helliwell (1985), unpublished at the SRS and Rossmann et al. at Cornell unpublished (1986)). Data collection on some virus crystals is virtually impossible in the home laboratory. 

In the early days of virus crystallography at the synchrotron, the largest lattice constant dealt with was that of cow pea mosaic virus (Usha et al 1984). This virus crystallised in space group P6j22 (or its enantiomorph) with a=451 A and c=1038A. Data collected at LURE (figure 10.18) were analysed and the results showed that quality data... 

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