Versus octanol-water partition coefficient

Figure 7.39 Intrinsic permeabilities (iso-pH data analysis) versus octanol-water partition coefficients.

Fig. 14 Bioaccumulation factor (BAF) in Lake Superior lake trout versus octanol-water partition coefficient (.Kow) for 19 toxaphene congeners plus B9-715 and B10-1010 [74], Results for 6 congeners (P31, B8-1413, B9-1679, B9-1046, B9-715 and B10-1010) were estimated assuming water concentrations at the detection limit. The coefficient of variation r2 = 0.35 P< 0.01...

Figure 10.10 Aqueous solubility (SJ versus octanol-water partition coefficient (/fow) foi" a variety of organic solutes. Note that highly soluble compounds are poorly sorbed and vice versa. Reprinted with permission from Chiou et al. Envir. Sci. Technol. 11 475-477. Copyright 1977 American Chemical Society.

Figure 190. A log-log plot of sorption number (S into a PVC container versus octanol-water partition coefficient (PWmd) for a number of drugs. Drugs were stored at 15-20°Cfor 1, ( ) and 24 h ( ). (Reproduced from Ref. 750 with permission.)...

FIGURES Plot and least square regression of estimated normalized bioconcentration factors (log NBCF, TABLE 3) versus octanol/ water partition coefficients (log P) for 11 chemicals. 

Fig. 3.2. Log of%mole fraction membrane retention versus log of apparent octanol/water partition coefficient at pH 7.4. Microfilters were impregnated with 2% wt/vol DOPC in dodecane.

FIGURE 1.7.3 Octanol-water partition coefficient versus Le Bas molar volume for mononuclear aromatic hydrocarbons. 

FIGURE 1.7.5 Octanol -water partition coefficient versus molar solubility (liquid or supercooled liquid) for mononuclear aromatic hydrocarbons. 

The most notable correlation found for the organic carbon partition coefficient (Koc) of hydrophobic chemicals is that obtained with the octanol/water partition coefficient (Kow). Recently, a single correlation has been proposed for all these compounds based on previous data (log(Koc/Kow) versus logAow) the specific approximation proposed was Koc = 0.35 Kow, but this could vary by a factor of 2.5 in either direction [39]. 

For example, such a relationship can be seen to apply to the data of Hutchinson et al. (1978), who reported the concentrations of numerous apolar and slightly monopolar compounds to inhibit microalgal photosynthesis by a factor of 2. When the effective concentrations (in mol L-1) are examined versus each compound s octanol-water partition coefficients, one finds the following relations ... 

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