Ventilation systems avoidance

Although metallic antimony may be handled freely without danger, it is recommended that direct skin contact with antimony and its alloys be avoided. Properly designed exhaust ventilation systems and/or approved respirators are required for operations that create dusts or fumes. As with other heavy metals, orderly housekeeping practice and good personal hygiene are necessary to prevent ingestion of (or exposure to) antimony. 

Start-up of the exhaust ventilation system and critical equipment must be sequenced to prevent a hazardous condition. In addition, the starting of the supply air handling unit and the exhaust fan services each room shall initiate simultaneously to avoid placing the room under positive pressure. Automatic transfer switching will be used. 

Facilities should be designed to avoid disturbances such as intermittent or continuous noise from within or outside the facdity, frequent traffic in and out of animal rooms, obnoxious odors (e.g., chemical odors that are carried by ventilation systems from laboratories to animal housing areas). 

Vapur-phase activated carbons are also used for deodorizing air in ventilation systems, treating exhaust gases from manufacturing plants to avoid contamination of the atmosphere, and of coorse in gas masks. 

Having defined the hazardous areas it may be possible to reduce their extent. For instance, a ventilation system can be used to pull air into the vessel through the chargehole, and this will reduce the size of, or eliminate, the hazardous area outside the vessel a sealed system can also be used (whenever possible a sealed system using a mechanical device for the remote charging of the powder is always to be preferred over manual addition through a chargehole). It is unlikely that ventilation can be used to avoid a flammable atmosphere inside the vessel as the air flow necessary would evaporate too much solvent. 

An appropriate general ventilation system (see C4 below) with air intakes and exhausts located so as to avoid intake of contaminated air (194) ... 

In the available investigations on a potash mine ventilation system (De Souza 2006), the features of airflow were analyzed and the barriers of the ventilation network were identified. The work by Tiley authors was to detail the conveyance motion with the criterion to avoid collision between conveyances or between conveyance and shaft. Based on the running clearance... 

The final vent from the system should be regarded as a point of possible chlorine emission. It should be at a high level and away from personnel traffic and ventilation system intakes. Particularly when the low-pressure scrubbing device is a packed bed, booster fans may be added on the tail pipe. The piping arrangement around the fans then should avoid low points that could collect liquid. As with any vent manifold, the designer of a system serving several different units should take precautions to avoid mixtures in headers that may lead to undesirable side reactions. 

The cleaning of heating radiators is very laborious and not very feasible in practice. Therefore, they are unsuitable for pharmaceutical preparation premises. If they nevertheless caiuiot be avoided, sheet radiators mounted at sufficient distance from the wall to allow effective cleaning, are to be preferred. However, in GMP classified premises as meant in Sect 27.4.2 even sheet radiators are absolutely undesirable. Heating and cooling in that case should be achieved by means of the ventilation system (see Sect. 27.5.1). 

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