Nicholas-Vauquelin, Louis

The nicotine molecule consists of a pyrrolidine ring attached to a pyridine ring by a bond between carbon atoms in the two-ring systems. Nicotine was isolated in impure form from tobacco in 1809 by Louis Nicholas-Vauquelin (1763—1829). Vauquelin called the substance nicotianine. In 1826, Wilhelm Posselt (1806-1877) and Karl Ludwig Reimann (1804-1872), medical students at Heidelberg University, isolated pure nicotine and published dissertations on its pharmacology in 1828. Louis Henri Melsens (1814—1886) determined nicotines empirical formula. Ame Pictet (1857-1937) and P. Crepieux reported the synthesis of nicotine in 1903. 

French chemists Louis-Nicholas Vauquelin and Pierre-Jean Robiquet isolate asparagines, the first amino acid to be discovered. 

Petit formulate the Dulong-Petit law in solid elements the product of the specific heat and the atomic mass is a constant. French chemist Louis-Nicholas Vauquelin isolates cyanic acid. 

Chromium (Cr, [ArP s1), name and symbol after the Greek xpio(ia (chroma, colour). Discovered (1780) by Nicholas Louis Vauquelin. 

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