Vascular formation

Kirchengast M, Witte K, Stolpe K, Schilling L, Nedvetsky PI, Schmidt HH, Lemmer B. 2005. Effects of chronic endothelin ET(A) receptor blockade on blood pressure and vascular formation of cyclic guanosine 3 5 monophosphate in spontaneously hypertensive rats. Arzneimit-... 

Resisting vascular wall cell migration and hyperplasia. Vascular EC can be induced to resist SMC invasion. For this mechanism, besides the functions of EC-produced multiple factors, EC itself is also capable of migration with the cue of migrating factors secreted by platelets or leukocytes and the shear stress by blood flow. EC migration usually accompanies proliferation, which frequently relates to new vascular formation or defective vascular regeneration [100,101]. 

A porosity exceeding 90% and an open micropore geometry to ensure cell growth and migration into the inside. Micropores make both vascular formation and nutrients and metabolic product flow ... 

The content of thermospermine in individual plants is several fold lower than that of spermine in Arabidopsis (Naka et al. 2010 Rambla et al. 2010), mainly because ACL5/TSPMS expression is sharply limited to xylem precursor cells during vascular formation (Qay and Nelson 2005 Muniz et al. 2008). Because the mutated... 

They release adenosine diphosphate [58-64-0 (ADP) and thromboxane [57576-52-0] which results in vascular contraction and, indirectiy, in the formation of fibrin clot. Platelet transfusions are indicated for patients with thrombocytopenia, ie, a shortage of healthy platelets or thrombocytopathy, ie, platelet malignancy associated with spontaneous hemorrhages. 

Lead is toxic to the kidney, cardiovascular system, developiag red blood cells, and the nervous system. The toxicity of lead to the kidney is manifested by chronic nephropathy and appears to result from long-term, relatively high dose exposure to lead. It appears that the toxicity of lead to the kidney results from effects on the cells lining the proximal tubules. Lead inhibits the metaboHc activation of vitamin D in these cells, and induces the formation of dense lead—protein complexes, causing a progressive destmction of the proximal tubules (13). Lead has been impHcated in causing hypertension as a result of a direct action on vascular smooth muscle as well as the toxic effects on the kidneys (12,13). 

Yancopoulos GD, Davis S, Gale NWetal (2000) Vascular-specific growth factors and blood vessel formation. Nature 407 242-248... 

The calcification of atherosclerotic plaques may be induced by osteopontin expression, since osteopontin is a protein with a well-characterized role in bone formation and calcification. Vascular smooth muscle cell migration on osteopontin is dq endent on the integrin av 33 and antagonists of av 33 prevent both smooth muscle cell migration and restenosis in some animal model [8]. 

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