Vacuum drying system

The vacuum plate drwer is provided as pari of a closed system. The vacuum dryer has a cylindrical housing and is rated for fiill-vacuum operation (typical pressure range 3-27 kPa absolute). The exhaust vapor is evacuated try a vacuum pump and is passed through a condenser for solvent recovery. There is no purge-gas system required for operation under vacuum. Of special note in the vacuum-drying system... 

Anon. Crux vacuum drying system—technical information. Micron Powder Systems-Hosokawa Micron Group, 1994b. 

Anon. Crux Vacuum Drying System. Bulletin Cl. Orient Chemical Ind. Ltd. Hosokawa Micron Group, 1995a. 

Maekawa Y. Instantaneous vacuum drying system. In Rudolph V, Keey RB, eds. Drying 94. Proc. Inti. Drying Symposium (IDS 94), Gold Coast, Australia, 1994a, pp 359-366. 

Moisture is removed from the canister using a vacuum drying system or forced helium dehydration system. For canisters without high bum-up fuel, the vacuum drying system may be connected to the canister and used to remove all liquid water from the canister in a stepped evacuation process. A stepped evacuation process is used to preclude the formation of ice in the canister and vacuum drying system lines. The internal pressure is reduced to below 3 torr and held for 30 min to ensure that all liquid water is removed. 

Brouwers J, Brewster ME, Augustijns P (2009) Supersaturating dmg dehvery systems the answer to solubilityaLllimited oral bioavailabihty J Pharm Sci 98 2549-2572 Chiang P-C, Ran Y, Chou K-J, Cui Y, Sambrone A, Chan C et al (2012) Evaluation of dmg load and polymer by using a 96-well plate vacuum dry system for amorphous solid dispersion dmg dehvery. AAPS PharmSciTech 13 713-722... 

When water is used as granulation liquid for effervescents, the effervescent reaction will start and cause a chain reaction. The critical point in such a process is to stop this reaction at the correct time by evaporating the water created by this reaction. In a single-pot processor, this can be very easily and accurately achieved by switching on the vacuum-drying system (possibly supplemented with gas-assisted drying or microwave drying) (24). 

Drying of the single-pot processor after the cleaning cycle to prepare the equipment for the next batch can be done using the system s own vacuum-drying system and jacketed bowl, making a separate drying unit redundant. 

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