Uvomorulin

J Behrens, W Birchmeir, SL Goodman, BA Imhof. (1985). Dissociation of Madin-Darby canine kidney epithehal cells by the monoclonal antibody anti-arc-1 Mechanistic aspects and identification of the antigen as a component related uvomorulin. J Cell Biol 101 1307-1315. 

WJ Nelson, EM Shore, AZ Wang, RW Hammerton. (1990). Identification of a membrane-cytoskeletal complex containing the cell adhesion molecule uvomorulin (E-cadherin), ankyrin, and fodrin in Madin-Darby canine kidney epithehal cells. J Cell Biol 110 349-357. 

B Gumbiner, K Simons. (1987). The role of uvomorulin in the formation of epithehal occluding junctions. In Anonymous. Junctional Complexes of Epithehal Cells, CIBA Foundation Symposium 125, New York Wiley, pp 168-186. 

The transition from mesenchyme to epithelium involves biochemical changes in the cells and the extracellular matrix, N-CAM expression on cell surfaces disappears, replaced by L-CAM (uvomorulin). Vimentin, a characteristic cytoskeletal component of mesenchyme, disappears, and cytokeratin, characteristic of epithelia, appears. There is a decrease in collagen I extracellularly and an increase in the basement membrane components laminin and collagen IV. 

E-cadherin (epithelial) L-CAM, uvomorulin Early embryo (blastula epiblast cells)... 

Le Bivic, A., Sambuy, Y., Mostov, K., and Rodriguez-Boulan, E. (1990) Vectorial targeting of an endogenous apical membrane sialoglycoprotein and uvomorulin in MDCK cells. J. Cell Biol. 110, 1533-1539. 

Vestweber, D., Gossler, A., Boiler, K., and Kemler, R. 1987. Expression and distribution of cell adhesion molecule uvomorulin in mouse preimplantation embryos. Dev Biol 124(2) 451-6. 

Vestweber, D. and Kemler, R. 1984. Some structural and functional aspects of the ceU adhesion molecule uvomorulin. Cell Differ 15(2-4) 269-73. 

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