Use as Protecting Groups for Diols and Diamines

Use as Supports for Derivatization and Affinity Purification of Diois, Sugars, and Ciycosyiated Proteins 

The concept of immobilizing diol compounds with a boronic acid conjugated support as a sort of heterogeneous protecting group strategy is the antipode of the diol-based supports described in Section 1.4.2. Examples of such boronic acid matrices include polystyryl boronic acid resins (120) [500-502], the cellulose-derived support 121 [503], the methacrylic polymer 122 [504], and the polyacrylamide-supported nitroarylben- 

Use as Receptors and Sensors for Carbohydrates and other Small Molecules 

Mixed receptors containing boronic acids and charged functionalities were also developed for the recognition of sugar acids [517] and even for heparin [311], a polysul-fated saccharide. Boronic acids also interact strongly with a-hydroxycarboxylic acids [518], and receptors selective for tartrate were reported [519], 

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